Best cbd oil for arthritis in humans

10 Best CBD Oils for Arthritis [Exclusive Review]

Those living with arthritis can sometimes experience debilitating pain. For individuals going through this constant cycle of discomfort, a 24-hour period with slight relief can make all the difference in the world.

Conventional pharmaceutical medications (anti-inflammatories, painkillers, etc.) are often paired with negative side effects. These drugs are often as difficult to live with as arthritis itself.

Thinking about using CBD oil for arthritis? The first thing you should know is not all oils are made the same…

For those with arthritis, CBD oil has emerged as a potential alternative to conventional medication. Many arthritis patients have discussed the relief that CBD oil has provided. In turn, this has encouraged other patients with arthritis to make the switch.

This article looks at recent medical research into CBD for arthritis and offers advice on finding the best cannabidiol product for your needs.

Below you will find our selections for the 10 Best CBD Oils for Arthritis. Each CBD brand was thoroughly tested according to efficiency, potency, transparency, and price.

Benefits of CBD Oil for Arthritis Patients

For arthritis patients specifically, the benefits of CBD oil stem from the compound’s anti-inflammatory properties.

Patients with arthritis can administer CBD (cannabidiol) in several ways, including oral consumption (tincture drops), capsules, and topical CBD-based gels and creams. However, for people with arthritis, rubbing a topical CBD formula on inflamed joint areas is one of the most popular forms of application.

While people of all ages have reported success stories, it’s important to point out that CBD is not an FDA-approved treatment for arthritis. As such, be wary of companies selling CBD oil that claim to treat or cure any form of arthritis or joint pain. These claims are unfounded and not supported by clinical data.

Even so, we’d thought we would share a few comments from people who tried CBD for arthritis and were thrilled with the results.

Independent Reviews of CBD Consumers

“I am 62 years old and have suffered from painful and sometimes even immobilizing arthritis, specifically in my wrists and elbows. I tried many conventional medications that the doctor prescribed to me and began experiencing horrible side effects. About a year ago, I decided to switch to CBD oil. I began ingesting drops orally, as well as rubbing the gel into my joints. The results have been miraculous, and I am now able to function better than I have in years.”

-Summer Andrews

“I have been able to mostly cut out my use of opioid painkillers and anti-inflammatory drugs thanks to CBD oil extracts. It feels great to be relying more on nature than on pharmaceuticals to assist my knees and ankles, the regions of my body that seem to be taking the most damage from the arthritis.”

-Gerry Burlington

Next, let’s outline why CBD is potentially useful for patients with arthritis.

Is CBD Oil Good for Arthritis?

A growing number of people think the answer is ‘yes.’ According to an Arthritis Foundation poll, almost 30% of respondents currently use a CBD product, mainly a topical or liquid. Moreover, nearly 80% were either using CBD, had tried it in the past, or considered it for arthritis pain.

Also, in this poll, 87% of respondents said they used CBD specifically to manage their arthritis symptoms, with 94% saying they tried cannabidiol to relieve pain. Of those currently using CBD, 67% reported improved physical function, while over 30% said it provided relief from morning stiffness.

There is a suggestion that CBD’s anti-inflammatory effects could help slow down the progress of rheumatoid arthritis (RA) or even halt it. CBD might also positively impact inflammation-related RA symptoms, such as fever and fatigue, by preventing RA from damaging the joints.

CBD has a different effect on the brain than THC and is non-intoxicating. It interacts with the CB1 and CB2 receptors in the body’s endocannabinoid system (ECS). This interaction could help reduce the effects of inflammation, including pain. A growing body of evidence suggests the effects of CBD on arthritis are indeed beneficial.

For instance, this study published in the European Journal of Neuroscience in 2014 found that the ECS was involved in osteoarthritis pain. Since CBD and other cannabinoids impact the ECS, it is entirely possible that using them for arthritis is beneficial.

Let’s check out some more research.

Medical Research on CBD Oil for Arthritis

While there are some older studies into CBD’s possible effects on arthritis, it is best to focus on more recent data. A study published in the European Journal of Pain in 2016 looked at how CBD gel helped lab rats with induced arthritis. The researchers applied CBD gels to the rats for four consecutive days in concentrations of 0.6, 3.1, 6.2, or 62.3mg per day.

Overall, they found that 6.2mg and 62.3mg were “effective doses.” This suggests that arthritis patients only need to apply a consistent and reasonable quantity of CBD to feel an effect.

Research investigating the link between CBD and arthritis pain is positive; however, most studies test on animals.

A 2017 study published in Pain analyzed the effect of CBD on rats with induced osteoarthritis (OA). The researchers found that local administration of CBD blocked pain. Also, prophylactic CBD treatment prevented pain and nerve damage in the OA joints from developing later on. The team wrote that “CBD may be a safe, useful therapeutic for treating OA joint neuropathic pain.”

More recently, a study published in Cell Death & Disease in 2020 also revealed positive news regarding CBD and arthritis. The abstract states that CBD had anti-arthritic activity and could reduce symptoms by “targeting synovial fibroblasts under inflammatory conditions.”

Hopefully, we will receive information from clinical studies that show CBD’s positive effect on arthritis in human patients sooner rather than later.

Now, let’s look at the brands worth considering when you’re on the hunt for CBD oil for arthritis.

Don’t want to read our #1 CBD brand for this year? Check out the video summary below on the best CBD oil for arthritis!

10 Best CBD Oils for Arthritis

The following is a top-10 list of the best CBD oils for arthritis. We feel these products are of the highest quality currently available on the market. Please remember that none of these products are FDA-approved treatments for arthritis. They should not be considered a cure or treatment for the condition.

In 2018, a World Health Organization (WHO) critical review report stated that CBD oil is generally well tolerated with a good safety profile. However, it can still lead to adverse side effects. Therefore, we recommend discussing your use of CBD with a healthcare professional before implementing any new products into your day-to-day regimen.

1. PureKana

First on our list is PureKana. This brand is a leading CBD oil manufacturer featured by major industry publications such as High Times. As one of the best-known CBD oil producers, its products are very trustworthy. By utilizing state-of-the-art CO2 extraction techniques, PureKana can create one of the purest CBD oils.

BENEFITS OF PUREKANA CBD OIL
  • Non-intoxicating
  • Organic and non-GMO
  • Fast delivery with free shipping
  • Potencies ranging from 300mg – 2,500mg
  • Full Certificates of Analysis (COAs) are available on the PureKana site

Visit the official online store at www.purekana.com.

Also, don’t forget to use our coupon to get 20% off your order: 20KANA

2. Charlotte’s Web CBD Oil

Charlotte’s Web is one of the best-selling CBD oil brands in the USA. Its quality has kept it ranked among top consumer lists for several years. CW Hemp offers a complete range of high-quality CBD oils, as well as hemp-infused CBD creams and balms. Most importantly, these creams contain pure, potent CBD extract, and you can administer them directly at the site of discomfort and inflammation.

BENEFITS OF CW HEMP CBD OIL
  • Full-spectrum extract includes terpenes and other active phytocannabinoids (CBC, CBG, CBN)
  • Various potencies available
  • One of the best-selling CBD oils in the U.S.

For more information on the complete range of CW Hemp products, visit the official website at www.charlottesweb.com.

Also, feel free to read our comprehensive Charlotte’s Web Review to learn more about its products.

3. Premium Jane CBD

Premium Jane sells four different products, each one crafted with care and expertise. For example, it sources its hemp from farms in Kentucky, with every batch tested by a reputable laboratory. Premium Jane currently offers full-spectrum CBD oil tinctures with cannabidiol concentrations of up to 5000mg, CBD gel capsules, topical CBD cream, and CBD gummies.

BENEFITS OF PREMIUM JANE CBD OIL
  • Sourced from genetically selected CBD hemp plants
  • The hemp is harvested from organic USA farms
  • Six available flavors: Natural, Citrus, Mint Chocolate, Mint, Lemon Lime, and Peach Nectar
  • Full-spectrum CBD oil includes terpenes and phytocannabinoids

If you’re living with arthritis, browse the selection of Premium Jane CBD oils and topical creams at www.premiumjane.com.

Also, be sure to use our 20% Coupon Code: 20JANE

4. Hemp Bombs

Hemp Bombs is a unique CBD brand out of Tampa, Florida. It offers a large selection of products for various uses, including CBD edibles, CBD vape additives, and more. Hemp Bombs also formulate potent full-spectrum tinctures. The 5000mg bottle offers 166.67mg of CBD per ml.

BENEFITS OF HEMP BOMBS CBD OIL
  • Large range of CBD products and potencies to choose from
  • Consistent engagement with its client base
  • Frequent discounts and online promotions
  • Products are available in retail locations across the U.S.
  • Offers compliance labels and lab reports on every one of its products

Shop the entire selection of CBD products over at www.hempbombs.com.

5. CBD Essence

CBD Essence offers a wide array of CBD-based products ranging from vape juices to CBD candy. Easily accessible items include hemp oil capsules and pet CBD oil. The diversity in items sold by CBD Essence makes it one of the top brands on our list.

BENEFITS OF CBD ESSENCE CBD OILS
  • Safe for both human and pet consumption
  • Products sourced from EU-certified industrial hemp
  • Delivers to all 50 states plus U.S. territories

To discover the benefits of each product, check out our CBD Essence online review.

6. FAB CBD

FAB CBD offers a variety of flavorful CBD tinctures. Its CBD products are sourced from hemp with a THC content of less than 0.3%. This potent, high-quality range offers a robust full-spectrum extract of plant phytocannabinoids. It also offers other CBD options, such as chews and topicals, for those who dislike placing the oil drops under their tongue.

BENEFITS OF FAB CBD OIL
  • FAB CBD sells isolate options that are 100% THC-free
  • Lab-certified and free from any chemical solvents
  • Made in the USA
  • Entry-level CBD options for all budgets

Learn more about the complete range of FAB CBD products at www.fabcbd.com.

7. Joy Organics

Joy Organics CBD is another firm favorite here at WayofLeaf. This long-standing brand offers a variety of high-quality CBD oil products that are trustworthy and safe for oral consumption. The products are versatile and should suit your needs regardless of why you use CBD.

Joy Organics has become a leader in the CBD industry largely due to its rock-solid reputation and effective, reliable hemp extract products.

BENEFITS OF JOY ORGANICS CBD OIL
  • Farm Bill compliant
  • Money-back guarantee
  • Broad-spectrum (zero THC) formulas
  • Sourced from USA-grown hemp

Access Joy Organics CBD products online at www.JoyOrganics.com, or feel free to read our Joy Organics Review.

8. CBDPure

By keeping its product line simple and unadulterated, CBDPure focuses on quality. Because of this, the hemp it uses is certified organic and originates from Colorado and Washington. All products are analyzed via an independent third-party laboratory. Also, you can view these COAs on the brand’s official website.

BENEFITS OF CBD PURE CBD OILS
  • Satisfaction guarantee and 90-day return policy
  • Produced with certified organic hemp
  • Free of solvents, heavy metals, and other contaminants
  • Independent third-party lab testing for quality
  • Full-spectrum of plant-based cannabinoids and phytochemicals

To discover more about CBDPure, visit its website at www.cbdpure.com.

9. CBDistillery

Most people recommend an oral CBD oil or a topical CBD cream for arthritis. However, CBDistillery specializes in high potency isolates that you can use as dabs or with a portable vape pen. Its tinctures range from a CBD concentration of 500mg to 5000mg.

BENEFITS OF CBDISTILLERY CBD OILS
  • Lab reports with CBD content posted on each product page
  • Full-spectrum tinctures
  • Frequently mixed with juice or coffee for easy ingestion

Check out our Full Review of CBDistillery and learn why it belongs on our top 10 list.

10. Elixinol

Many media sources, including Men’s Health, The Wall Street Journal, and CNN, recognize and feature Elixinol. Most importantly, these outlets praised the CBD oil company for its top-quality products, which offer purity and potency.

BENEFITS OF ELIXINOL CBD OIL
  • Organic hemp extract tinctures
  • Excellent product variety and versatility
  • Praised for purity, potency, and clarity
  • Affordable pricing

Make sure you use our 15% off coupon if you order online: 15CBDOFF

CBD OIL FOR ARTHRITIS – WHERE TO START?

As you can see, there are several top-quality CBD oil producers on the market. We conducted hands-on research and carefully reviewed a number of these products. Ultimately, we decided to choose the one we believe surpasses the others regarding quality, accessibility, and purity. From what we’ve seen, PureKana brings an impeccable line of CBD products to the market.

  • Official website link: purekana.com
  • 20% coupon code: 20KANA

Even if you do not choose to go with PureKana, know that all of the companies listed above have top-notch products, and most offer a 100% money-back guarantee. Therefore, it is likely that you will be happy with your product.

CBD Oil for Arthritis Uses

One of the great benefits of CBD is its versatility. People with arthritis have many options when it comes to using it. Generally speaking, the best CBD products for joint pain and similar conditions are topicals such as creams, balms, and ointments. These products are infused with cannabidiol and are easy to rub into the skin at the site of pain.

According to many CBD topical users, products tend to work relatively quickly and can provide relief for hours. Also, the bioavailability of topicals is likely on the high side, although there are few studies to confirm this.

Topical products tend to work relatively quickly and can provide relief for hours. Some prefer vaping the cannabinoid for fast-acting effects.

Edibles and tinctures are standard CBD products but aren’t always the best option. You might find edibles take too long and have a low absorption rate. CBD oils tread the middle ground as they can take effect relatively quickly and offer a reasonable rate of bioavailability.

Individuals using CBD for arthritis might want to try vaping the cannabinoid if they need a fast-acting product. Some users say they feel the benefits within seconds, and the absorption rate is relatively high. However, there are concerns over the long-term safety of vaping products.

CBD Dosage for Arthritis

Unfortunately, there is no standard CBD dose, given the lack of industry regulation. You can look for dosing guides online, which tend to recommend using a specific amount depending on your body weight. Certainly, the amount you weigh plays a role in how the cannabinoid affects you.

Yet, we feel that the best course of action is to first begin with a small amount of CBD. Monitor how you feel in general and determine whether the cannabinoid has a positive effect. If you feel nothing, slowly increase the amount you use until the effect is noticeable. Also, please remember that you need to use CBD consistently for a couple of weeks to get the best effects.

Best CBD Oil for Arthritis: What to Consider

One of the biggest issues when purchasing any CBD product for arthritis is the lack of industry regulation. As long as CBD isn’t a federally legal substance, the FDA will provide little oversight. Typically, the FDA does nothing other than send warning letters to brands that make medical claims.

Otherwise, you’re relying on state laws which are not always detailed. As a result, virtually anyone can create a CBD brand overnight and begin selling low-quality, potentially harmful products. Here are six things to consider before investing in any CBD products.

1 – Where Does the Hemp Come From?

Although hemp has many benefits as a crop, one of its big strengths is potentially a weakness. Hemp absorbs a huge amount of the elements in the soil. This is great news when it is cultivated organically in high-quality soil. However, if grown in contaminated land, hemp absorbs the toxins. Sadly, some companies use low-grade hemp when creating CBD.

Therefore, you should stick with brands that only use organically grown hemp from the United States, Canada, or Europe.

2 – Extraction Method

Let’s keep this short. Steer clear of brands that use a solvent like butane, hexane, or propane. Certain reputable brands use food-grade ethanol extraction as they claim it results in a product with more terpenes and cannabinoids. This is okay as long as they remove the vast majority of the residual solvent.

However, there is a growing trend towards supercritical CO2 extraction. The carbon dioxide acts as the solvent, resulting in a clean, high-quality hemp extract.

3 – Type of CBD

There are three main types of CBD products:

  • Full-Spectrum: Contains dozens of cannabinoids and terpenes.
  • Broad-Spectrum: Also contains a wide array of compounds but little or no THC.
  • Isolate: CBD is the only cannabinoid in such products, although some brands add terpenes.

Much is written about the ‘entourage effect,’ with research suggesting that cannabinoids work better together than in isolation. However, data also says the notion of an entourage effect having a greater therapeutic effect is overblown.

Further studies into the phenomenon are necessary to get a clearer picture.

4 – Consumption Method

You can consume CBD in a variety of ways:

  • Orally: You eat a product such as a CBD chocolate bar, gummy, or capsule.
  • Sublingually: This involves placing CBD oil drops beneath the tongue and holding the liquid there for up to 60 seconds.
  • Vaping: A vaping device heats the CBD oil or concentrate, turning it into a vapor that you inhale.
  • Topicals: There are dozens of creams, balms, ointments, and sprays infused with CBD. Rub the substance into the skin to potentially benefit from localized relief.

As we mentioned earlier, most people will choose a topical product when using CBD for arthritis. However, you might find that a vaporizer provides rapid effects and a higher rate of bioavailability.

5 – Certificates of Analysis (COAs)

The COAs provided by a brand after conducting third-party testing are essential. This documentation enables you to see the CBD content of the product. It also shows the concentration of other cannabinoids and terpenes, not to mention evidence that the product is free from harmful chemicals.

Ensure the COAs are up to date and come from a reputable laboratory. Steer clear of any brand that doesn’t provide third-party lab reports.

6 – Brand Reputation

These days, it is hard to get away with deception for long. Check out customer reviews, as well as third-party reviews. While certain new brands are unquestionably legitimate, when in doubt, stick with companies such as PureKana that have been around for a while.

Final Thoughts on the Best CBD Oils for Arthritis

In conclusion, numerous reputable CBD products may offer anti-inflammatory properties. These properties may provide beneficial effects for various medical conditions, including arthritis.

Also, as an antioxidant, CBD could reduce the stressors that exacerbate inflammation. Properly-dosed CBD might improve general well-being, and it has little to no adverse side effects.

In summary, if you are an individual suffering from the debilitating pain of arthritis and are searching for an alternative option to relieve pain and discomfort, CBD oil could be an option. However, don’t expect any of the products listed above to “cure” your arthritis. Overall, countless people have found effective relief for their joint pain, but CBD oil has a unique effect on every individual.

We hope you have enjoyed reading about the 10 Best CBD Oils for Arthritis and that you have found this article to be educational and informative. Here is our final roundup:

Best CBD Oil for Arthritis: Benefits & Uses for Rheumatoid Arthritis

As many as 54 million Americans are diagnosed with arthritis every year. According to NHIS data, it’s the leading cause of work disability leave in the United States.

Arthritis can be a real pain — literally and figuratively. The disorder often brings a lowered quality of life for those affected, forces people to take time off work, and makes it difficult to exercise and remain in good shape. Many people are therefore looking for an effective form of pain management to help with the disorder.

See also  Letter of necessity cbd oil for anxiety sample

One of the most popular arthritis-supportive supplements being used today is cannabidiol (CBD) — one of the primary active ingredients in the cannabis plant.

Can CBD really help with arthritis? What’s the best CBD oil for arthritis?

We’ll explore these questions in detail in the article below. I’ll give you my top 5 CBD oils for arthritis pain, and give you some valuable insight into how to choose the best CBD oils for the job on your own.

This is a big topic so let’s dig in.

Best CBD Oils for Arthritis: Our Top 5 Brands of 2022

If you’re reading this article, you’re probably interested in finding a CBD product that can help you with your arthritis symptoms.

For those of you who want to understand how CBD works for arthritis, and what else you can do to make the effects of CBD even better, keep reading the sections below. If you’re simply looking for the best CBD oil to take, here’s a list of my top five CBD oils — including a breakdown of why I think it’s such a strong option.

Let’s dig into the list.

1. Royal CBD (Most Potent)

Get 15% off all Royal CBD products. Use code “CFAH” at checkout.

Technical Details:
Total CBD Content 250 – 2500 mg
Available Flavors Natural, Peppermint, Vanilla, Berry
Potency 8.3 – 83.3 mg/mL
What We Like About Royal CBD Oil:

A newcomer to the scene, Royal CBD is a premium manufacturer opting for high-grade organic ingredients in all its CBD products — including this full-spectrum hemp oil. The company’s product range is pretty simple, featuring only CBD oil, capsules, gummies, and some CBD-infused topicals.

The oil and capsules are full-spectrum extracts, while the gummies are made with a 99% pure CBD isolate. This oil has a few different options — you can choose between flavors like mint, berry, vanilla, or unflavored, and three separate potencies — 250 mg, 500 mg, 1000 mg, and 2500 mg of CBD per 30 milliliters (1 ounce) bottle. The strongest option carries 83.3mg of CBD in each milliliter.

For the best value, I recommend you aim for the higher potency option. This product has a higher initial cost than the others, but comes at a slight discount and will last a very long time — even if you use CBD on a daily basis. Only a few drops are needed to get a healthy dose of CBD.

If you don’t like the taste of natural CBD oil you can get their capsules instead. These come in an easy-to-swallow soft gel form and contain 25 mg per capsule.

All Royal CBD products are tested in third-party laboratories to ensure each batch is clean, has consistent levels of CBD, and is free from any potential contaminants.

  • Made with organic Colorado-grown hemp
  • All products are made with supercritical CO2 extraction
  • You can buy both full-spectrum and CBD isolate products
  • The highest potency bottle delivers 83.3 mg/mL
  • Every batch of product has been tested by a third-party laboratories
  • These products are priced on the higher end, although well justified

2. Gold Bee (Best Organic Formula)

Pros:
  • Made from US-grown, organic hemp
  • Contains full-spectrum CBD
  • 1200 mg of CBD per bottle (40 mg/mL)
  • Extracted with supercritical CO2
  • Delicious Kiwi flavor
  • Sweetened with organic honey
  • Third-party tested for cannabinoid content and purity
Cons:
  • Only one concentration available
  • Limited flavor options
What We Like About Royal CBD Oil:

When it comes to arthritis, the quality of ingredients is paramount, as any pro-inflammatory compound can actually worsen your symptoms. With Gold Bee, this isn’t a problem, as the brand sells all-organic CBD oils formulated with full-spectrum hemp extracts. The hemp used by the company comes from organic farms in Colorado and is gently extracted with supercritical CO2 to provide the highest purity and consistent potency.

The full-spectrum of cannabinoids means you’re getting the synergistic effects from all naturally-occurring compounds in hemp, including the supportive cannabinoids and terpenes. As a result, you need less CBD to achieve the desired results than you would with CBD isolate. The Gold Bee CBD oil packs 1200 mg of CBD in a 30-mL bottle, translating into 40 mg of CBD daily. The dosage fits within the most common range for daily use.

Gold Bee also doesn’t use artificial flavorings and sweeteners in its products. The kiwi version of the CBD oil is infused with natural terpenes and sweetened with organic honey from Brazillian rainforests. The entire Gold Bee product line is rigorously tested in third-party laboratories for potency and purity.

3. CBDPure

Technical Details:
Total CBD Content 100 – 600 mg
Available Flavors None
Potency 1.6 – 10 mg/mL
What We Like About CBDPure Hemp Oil:

CBDPure was founded in 2016 by cannabis aficionados from Colorado. The company has a simple mission — to make high-quality CBD oils made from organic hemp.

Although the company only sells CBD oil and capsules, it’s perfected both of these products. These extracts are made with supercritical CO2 and tested in third-party laboratories for quality assurance.

When it comes to CBDPure hemp oil, it isn’t as potent as those offered by Royal CBD — so if you’re looking for something high potency CBDPure may not be the best option available. However, if you want something cheap that maintains a high level of quality — CBDPure is an excellent choice.

CBDPure has an incredible return policy — which suggests the founders truly stand by their products. If you don’t like the product you can return it for 100% money back within 90 days. Most other CBD companies only offer this deal for 14 or 30 days, so this says a lot about the integrity of CBDPure as a company.

  • CBDPure products are sourced from organic hemp grown in Colorado
  • The company uses supercritical CO2 to make its extracts
  • 100% Satisfaction Guaranteed program (full refund within 90 days)
  • Narrow product range
  • The oil is slightly less potent than Royal CBD

4. Hemp Bombs

Technical Details:
Total CBD Content 300 – 5000 mg
Available Flavors Unflavored, Acai Berry, Orange Creamsicle, Peppermint, Watermelon
Potency 10 – 1166.6 mg/mL
What We Like About Hemp Bombs:

Hemp Bombs are one of the longest-standing companies in the CBD space. They’ve been around for years now, dating back before the CBD boom. As a result, the company has had a chance to become well-established in the industry, and have a loyal customer base as a result.

Although the branding makes these oils resemble a gas station brand of an energy drink — the oil contained inside is nothing to scoff at.

Hemp Bombs is able to use its large presence in the industry to source some of the best hemps in the country. They process all the hemp within the United States in GMP-certified labs. The company chose to use a CBD isolate for this oil rather than a full-spectrum extract. Using CBD isolate is cheaper and more accurate than full-spectrum products, but lacks the synergistic benefits of the entire cannabinoid and terpene profile — a concept referred to as the entourage effects.

The real benefit of using a CBD isolate is that this is the only way to guarantee the product contains no THC — which is the psychoactive cannabinoid responsible for producing the high from marijuana plants.

Hemp Bombs, like the others on this list, conducts extensive third-party testing on every batch of hemp extract that comes out of its facilities. This is the only way to ensure complete transparency and build trust with consumers. Hemp Bombs publishes these test results on the website for anybody to see — and includes the entire gamut of testing (heavy metals, cannabinoid profile, residual solvents, and microbial contaminant testing).

  • Made from high-grade CBD distillate
  • Comes in all different flavors and potencies
  • Third-party tested for transparency
  • Lacks the benefits of the entourage effect
  • Flavored with synthetic flavoring agents

5. Nuleaf Naturals

Technical Details:
Total CBD Content 240 – 4850 mg
Available Flavors None
Potency 48.5 mg/mL
What I Like About Nuleaf Naturals:

Nuleaf Naturals has the simplest product lineup I’ve ever seen. The company only offers one oil — a 48 mg/mL full-spectrum hemp extract. They use this same oil for every product offering.

When you go to the company website, you’ll find you can buy this oil in all different bottle sizes — but the oil itself is exactly the same. Even the pet oil options the company sells use this exact same extract.

The benefit of using just one oil is that Nuleaf Naturals can put all their attention and energy into this one product — doing everything they can to make it as top-notch as possible. And that’s exactly what they’ve done.

This oil is one of the best tastings and has some incredibly powerful effects compared to many of the other oils I’ve tried.

In order to even qualify for my top 5 list, the company has to offer third-party testing. I can’t trust the test results from a company doing their own testing. Nuleaf Naturals remains up to date with ordering third-party tests for every batch produced by the company. You’ll find a new test uploaded to the company website every two or three months as they release new batches of products. I have a look at these tests every time I order a bottle and have yet to find anything that stands out.

Every test I’ve seen from Nuleaf Naturals proves the oil is free from contaminants like heavy metals or pesticides, and the potency is almost always exactly the advertised potency. Occasionally a batch will come out that’s 2-5% off the advertised amount — which is expected for full-spectrum extracts.

  • Simple product lineup
  • Offers oils for both humans and pets
  • CBD oil comes in all different bottle sizes to support any budget
  • No flavor options available
  • All products use the same hemp oil

6. Medterra

Technical Details:
Total CBD Content 1000 – 2000 mg
Available Flavors Citrus
Potency 33.3 – 66.6 mg/mL
What I Like About Medterra:

This is a new product offered by the CBD giant Medterra. This company specializes in making broad-spectrum hemp extracts. This means the oil contains CBD, and most of the other supplemental cannabinoids like CBC, CBG, CBN, and THCV — but all traces of the psychoactive THC have been removed.

Medterra is intimately involved in the cultivation process for the hemp they use to make this oil — which allows the company to control the amount of pesticide used, and the timing of the harvest. These factors play a big role in the overall quality of the oil. Most other CBD companies buy hemp from farms located around the United States or Canada and have little control over the growing process.

Like any high-end CBD oil, this product has been thoroughly tested by both Medterras analysis lab, and independent laboratories.

Medterra sells a lot more than just CBD oils — you can also buy topicals, capsules, and pet treats.

  • Medterra has complete control of the entire manufacturing process from seed to bottle
  • Extensive third-party testing
  • Broad-spectrum THC-free hemp oil
  • Limited bottle sizes and flavor options
  • This oil is heavily processed

What is Arthritis?

Arthritis is one of the most common causes of disability in the United States. Millions of people in the United States alone suffer from debilitating joint pain and inflammation from arthritis.

The disease causes severe inflammation and pain, as well as swelling and loss of function in the joints.

There are two main types of arthritis:

  1. Rheumatoid arthritis — This form of arthritis is an autoimmune disease. This means that the cause of inflammation is triggered by our own immune systems. White blood cells mistakenly attack and destroy our own joint tissue, causing a cascade of inflammatory processes in the joints — causing them to swell up and feel hot and sore. This form of arthritis can affect any joint but tends to focus on the larger joints such as the knee, hips, elbows, and knuckles.
  2. Osteoarthritis — This form of arthritis is caused by physical trauma and wear and tear rather than the immune system. This form of arthritis is common in athletes and older people. The condition begins with a low-grade inflammation in the joint itself, which causes the degeneration of protective cartilage and synovial fluid (lubrication for the joints). As the joint tissue becomes damaged, inflammation and pain worsen and reduce the mobility of the joint. This condition is degenerative — which means it tends to worsen over time.

All forms of arthritis have the same basic symptoms — pain, inflammation, and reduced mobility of one or more joints. Despite having radically different underlying causes, CBD has become extremely popular among arthritis sufferers in recent years.

CBD Oil & Arthritis: Can it Help?

Let’s explore how CBD works, and why it’s become so popular among arthritis patients.

CBD is one of the active ingredients in hemp plants (Cannabis sativa). This phytochemical is completely non-psychoactive, which means it won’t cause the user to feel high. A related cannabinoid (THC) not found in high amounts in hemp plants is what causes marijuana users to feel high.

When CBD enters your bloodstream, it interacts with the endocannabinoid system — a complex neurochemical network responsible for maintaining various homeostatic functions in the body. This includes pain perception, immune response, temperature control, memory, mood, hunger, fertility, inflammation, and much more.

While research on CBD and arthritis is in the early stage, current evidence coming from animal studies and several human trials suggests it may alleviate the symptoms of arthritis while resulting in virtually no side effects.

Animal Studies on CBD & Arthritis

  1. A 2011 study discovered that CBD was able to reduce inflammatory pain in rats by changing the way pain receptors react to stimuli.
  2. A 2014 review of the existing animal-based studies concluded that CBD may be effective for relieving osteoarthritis.
  3. In a 2016 study, researchers found that CBD may relieve inflammation linked to arthritis in problematic areas when applied topically.
  4. A 2017 research paper suggested that CBD was a safe and effective treatment option for osteoarthritis joint pain.

The big question is whether these results can be replicated in actual human trials. Interestingly, this seems to be the case!

Clinical Trials on CBD & Arthritis

  1. In 2006, the first study on cannabinoids and rheumatoid arthritis concluded that a pharmaceutical CBD-enriched cannabis extract called Sativex had a “significant analgesic effect” in arthritis patients. Researchers reported that pain and inflammation were significantly reduced throughout the treatment despite having almost no reported side effects.
  2. A 2008 study involving cannabinoids in the management of chronic pain discovered that CBD offered effective pain relief and improved sleep quality in the test group.
  3. A 2016 analysis of human trials for rheumatoid arthritis, osteoarthritis, and fibromyalgia also found that CBD resulted in a reduction in joint pain and improvement in irregular sleep patterns caused by chronic pain.

CBD Oil For Sale: Where To Find High-Grade CBD Oil

Most people look for CBD oils online — myself included. Don’t get me wrong, it’s possible to find high-quality CBD oil in a local dispensary, but I’ve found online to offer a greater range of products, and quite frankly, better prices.

I recommend you check out the company websites listed in the section at the top of this article, or do your own research using the tips listed in the section below to find other reputable CBD brands online. Read reviews, and look for third-party testing before you buy the product to make sure it’s going to deliver on its promises.

Must-Know Details for People Buying CBD Oil for Arthritis

Knowing what to look for in the best CBD oil for arthritis will save you a lot of hassle — there are a lot of fly-by-night companies currently offering CBD oils with questionable quality, to say the least.

CBD is an emerging market, so it’s no wonder many companies want to capitalize on the booming trend before the dust settles and the industry stabilizes.

With such an abundance of different brands selling CBD in various forms, it’s important to find a trusted manufacturer who will ensure high standards for their products.

Here’s what you should pay attention to when shopping for CBD oil to help with your arthritis symptoms.

1. Hemp Source: Where is the Hemp Sourced?

Hemp plants are unique in that they will absorb and accumulate virtually any and all elements in the soil and air in which it’s grown — this includes both the good stuff and the bad stuff.

Plants grown in contaminated soils will often contain harmful levels of heavy metals like cadmium, lead, or mercury. For this reason, it’s important you look for products that have been grown in regions with little contamination — such as America or Canada.

Some companies source cheap hemp from India or China to cut costs — which are notoriously high in toxic heavy metal contaminants.

I prefer oils made from American-grown hemp because of the high standards here that prevent farmers from growing food or supplementing crops in contaminated soils or polluted air.

The best hemp comes from USDA-certified organic farms — but these are hard to come by at the moment.

2. Extraction Method: Did The Company Use Toxic Solvents to Make the Oil?

Most reputable companies use CO2 for making their CBD oil. Pressurized CO2 works as a solvent that pulls CBD and other compounds from the plant material. When the pressure is released, the CO2 evaporates completely, leaving no trace of harmful chemical solvents in the final product.

This is in opposition to the conventional extraction methods — which use toxic solvents to strip the cannabinoids from the plant material such as hexane, propane, butane, or ether. If these solvents are used they need to be evaporated out. Oftentimes, small amounts of these chemicals will remain in the final product which can cause many unwanted side effects to people using the oil.

3. Cannabinoid Spectrum: Could There be any THC in the Final Product?

The next thing to look at is the cannabinoid profile of the oil. This refers to the amount of CBD and other cannabinoids in the final product.

There are three main categories here:

  1. Full-spectrum extracts — these oils contain many different cannabinoids aside from just CBD
  2. Broad-spectrum extracts — these oils contain many cannabinoids with the exception of THC
  3. CBD isolates — these oils contain only one cannabinoid — CBD

Many experts argue that full-spectrum CBD oil is better for arthritis-related inflammation. A 2016 Israeli study found that unlike pure CBD isolate, full-spectrum extracts offered more reliable benefits for arthritis sufferers. However, there are benefits to using broad-spectrum or isolate-based products as well.

4. Route of Administration: How is the Oil Intended to be Used?

CBD comes in a few different forms and can be used in several different ways:

  1. Sublingual — placed under the tongue for fast absorption
  2. Edibles — helps mask the flavor of hemp oil bit has a slower onset of effects
  3. Vape liquids — used in vape pens to inhale the CBD for absorption via the lungs
  4. Topicals — applied directly to the skin for localized relief

Generally, the best CBD products for arthritis are going to be a combination of topical CBD and oral CBD. I rub CBD-infused joint cream on the affected area first and then use CBD oil sublingually for the fastest onset of effects. I know a few other people that prefer to use a CBD-infused vape pen and CBD topicals to relieve arthritis.

5. Third-Party Testing: Does the Company Provide Transparency for its Claims?

Every company has the option to send a batch of their product to a third-party laboratory for content analysis. In order to be considered a third-party lab, it needs to have no affiliation with the manufacturer — allowing for a completely unbiased assessment of the products in question.

These laboratories measure the potency of CBD, scan the entire cannabinoid profile of the product, and can detect over 200 common contaminants.

This form of testing offers transparency on the quality and potency of the product. If you can’t find third-party testing to confirm the CBD oil you’re looking at contains exactly what the company says it does — I recommend you look elsewhere until you find a company that publishes this data publicly. It’s the only way to ensure the product you’re buying is going to be safe and effective.

See also  Is cbd oil safe for eyes

What’s the Ideal CBD Dosage for Arthritis?

There is actually no one-size-fits-all dosage of cannabidiol when it comes to inflammatory pain caused by arthritis. The dose will vary a lot from one person to the next.

However, information gathered from CBD users suggests that most arthritis sufferers take around 25 mg of CBD in the form of an oil twice a day. You may need to increase or decrease this dose depending on how you respond to the oil. Most people shouldn’t expect any improvement in the first couple of days.

If you don’t feel any difference, gradually increase the amount of CBD oil until you find an effective dose.

Final Thoughts on Using CBD Oil for Arthritis

So far, research investigating the benefits of CBD oil for arthritis shows promising results. More research is needed to fully understand the role CBD and other cannabinoids play in alleviating arthritis-related pain and inflammation.

Although a large share of the studies currently available come from animal models. There are only a handful of good-quality clinical trials (double-blind and randomized). Of the few we have available in the scientific literature, all have shown notably positive results from the treatment group using CBD rather than placebo.

With all that said, it’s important to remember that CBD isn’t an overnight fix to all your problems, and in more serious cases, it may need some time to make the impact you’re looking for.

If you’re planning to use CBD oil for arthritis, consult your doctor first to discuss any potential interactions with other underlying health conditions or medications you may be taking.

Have you used CBD oil for arthritis symptoms? Post your results in the comment section below!

References:

  1. Schuelert, N. & Mcdougall, J.J. (2011). the Abnormal Cannabidiol Analogue O-1602 Reduces Nociception in a Rat Model of Acute Arthritis Via the Putative Cannabinoid Receptor Gpr55., Neuroscience Letters, 500(1), 72–76.
  2. La Porta, C., Bura, S.A., Negrete, R., Maldonado, R. (2014). Involvement of the Endocannabinoid System in Osteoarthritis Pain. The European Journal of Neuroscience, 39(3), 485–500.
  3. Philippot, H.T., O’Brien, M., McDougall, J.J. (2017). Attenuation of Early Phase Inflammation By Cannabidiol Prevents Pain and Nerve Damage in Rat Osteoarthritis. Pain, 158(12), 2442–2451.
  4. Blake, D.R., Robson, P., Ho, M., Jubb, R.W., McCabe, C.S. (2006) Preliminary Assessment of the Efficacy, Tolerability and Safety of a Cannabis-based Medicine (Sativex) in the Treatment of Pain Caused by Rheumatoid Arthritis. Rheumatology (Oxford), 45(1), 50–52.
  5. Russo E. B. (2008). Cannabinoids in the Management of Difficult to Treat Pain. Therapeutics and Clinical Risk Management, 4(1), 245–259.
  6. Fitzcharles, M.A., Baerwald, C., Ablin, J., Hauser, W. (2016). Efficacy, Tolerability and Safety of Cannabinoids in Chronic Pain Associated With Rheumatic Diseases (fibromyalgia Syndrome, Back Pain, Osteoarthritis, Rheumatoid Arthritis): a Systematic Review of Randomized Controlled Trials. Schmerz (Berlin, Germany), 30(1), 47–61.
  7. Gallily, R., Yekhtin, Z., Lumir, O.H. (2015). Overcoming the Bell-Shaped Dose-Response of Cannabidiol by Using Cannabis Extract Enriched in Cannabidiol. Pharmacology & Pharmacy, 6, 75–85.
Nina Julia

Nina created CFAH.org following the birth of her second child. She was a science and math teacher for 6 years prior to becoming a parent — teaching in schools in White Plains, New York and later in Paterson, New Jersey.

Leave a comment Cancel reply

Your email address will not be published. Required fields are marked *

Save my name, email, and website in this browser for the next time I comment.

Best CBD Oil for Pain Relief & Inflammation: Highest Quality Brands On The Market

Over the past three years, CBD oil has become increasingly popular as a health and wellness supplement.

One of the main reasons people are interested in trying CBD oil is because of its pain-killing benefits. We’ll get into the details of how CBD is suggested to help with pain later, along with some suggestions for the best CBD oils for pain and inflammation.

The ability for CBD to help with pain is a significant advantage over conventional pain management options — which often involve addictive and potentially harmful medications. Instead, this natural supplement has very few side effects and an exceptional safety profile — all without compromising on effectiveness.

But how do you choose the right CBD oil for the job?

This is an important question to ask because the truth of the matter is that not all CBD oils work. Many simply contain too little CBD to be of any help, while others contain harmful contaminants like heavy metals, pesticides, or chemical solvents — all of which could add to the pain you’re already experiencing by damaging the sensitive nerve cells around the body.

We’re going to cover all of this in the article below. You’ll learn how to spot a high-quality CBD oil and how current evidence shows CBD to work inside the body.

This is a big topic, so let’s get started with our list of top-rated CBD oils for pain.

Top 10 Best CBD Oil Brands for Pain Management in 2022

Not sure which CBD oil to buy to help with chronic pain? Before we get into the nitty-gritty of how CBD is suggested to work for pain and inflammation, here’s our top 5 list of CBD oils I’ve used myself for back pain.

We’ll also offer some advice on a few ways you can spot a trustworthy CBD vendor even if they didn’t quite make it onto our list.

I’ve been using CBD for over 5 years now and I’ve stumbled upon some stellar companies with top-notch oils and fly-by-night businesses with oils that can’t simply don’t work.

I have a relatively short list of CBD brands that I fully trust and I want to share my choices with you so you can avoid some of the headaches and disappointment I’ve already endured.

Here are my top 10 CBD oil brands for pain:

1. Royal CBD (Best CBD Oil On The Market)

Technical Details
Total CBD Content 250 – 2500 mg
Available Flavors Natural, Mint, Vanilla, Berry
Potency 8.3 – 83.3 mg/mL

Get 15% off all Royal CBD products. Use code “CFAH” at checkout.

Why Royal CBD is My Top Pick:

As skeptical as I am towards the majority of new CBD brands, I decided to give Royal CBD a try because I liked the company’s dedication to quality. I love seeing companies that take what they do seriously.

You can tell right away from the color, flavor, and consistency of the oil that you’re dealing with a product well above average.

This oil is cheaper than most of the other premium CBD oils I’ve tried, comes in a full range of potencies, and uses some of the best full-spectrum hemp extracts I’ve ever seen. I’ve heard friends using this brand for quite some time and decided to give it a try for myself — so I ordered a few bottles in different strengths.

After taking the Royal CBD’s 2500mg full-spectrum CBD oil for just over a week, I noticed an improvement in my back pain. There was a time when I had serious problems falling asleep because of the sharp pains in my back that seemed to intensify whenever I laid down to fall asleep. It was a nightmare. I’d lay awake for hours changing positions to try and find a spot that didn’t leave me writhing in discomfort.

With this oil, my experience went far beyond what I expected. Not only did it help ease the pain, but my overall quality of sleep improved. I mean, I didn’t sleep longer but I began to wake up rested and with a clear head.

My favorite combination for this particular oil is the vanilla in the 1000 mg bottle. This is the largest potency option currently offered by Royal CBD and has the best value overall. I took the oil twice per day, once in the morning when I woke up, and again in the evening before bed. One bottle of the 1000 mg CBD oil lasted me about a month.

  • Sourced from US-grown organic hemp
  • Extracted with supercritical CO2
  • Contains the full spectrum of cannabinoids and terpenes
  • Available in 4 different strengths
  • Up to 2500mg of CBD per bottle
  • Lab-tested for potency and purity
  • Great natural flavors (no aftertaste and comes in multiple flavor options)
  • Free shipping within the USA
  • Newer brand on the market that only sells online, no physical presence

2. Gold Bee (Best Organic CBD Oil)

  • Premium Colorado-grown hemp
  • CO2 extraction
  • Contains full-spectrum CBD
  • Delicious kiwi flavor
  • Sweetened with organic honey
  • Lab-tested for potency and purity
  • Only one flavored option available
  • No high-strength oils (yet)

What I Like About Gold Bee:

I honestly believe Gold Bee makes the best organic CBD products out there. The brand combines premium Colorado-grown hemp with organic honey sourced from the Brazillian Rainforest. While Gold Bee offers a modest selection of oils — with up to 1200 mg of CBD per bottle — the formula is spot-on when it comes to the quality of ingredients. I’m totally not going to complain about the potency, as my back pain and sleep quality got better than with some high-strength oils I’ve tried in the past. Considering the quality of these products, they actually come at a bargain price. If you want to try other formats from Gold Bee, you can choose between its high-strength capsules and CBD-infused honey.

3. CBDPure (Runner Up)

Technical Details
Total CBD Content 100 – 600 mg
Available Flavors None
Potency 1.6 – 10 mg/mL
What I Like About CBDPure CBD Oil:

I love how transparent this company is. If I were judging companies solely by their transparency level, CBDPure would have scored the second place, right after Royal CBD. The company provides all the details about each stage of production when making this CBD oil. You can find all the third-party lab test results for each batch on the product page — something we’ve come to expect from any high-quality CBD company.

What really makes this company stand out is its incredible satisfaction guarantee. If you order the product and decide it wasn’t working for you, simply send it back and get a full refund. This satisfaction guarantee extends over 3 whole months — which is about three times longer than the industry average.

I keep a bottle or two of CBDPure oil in my medicine cabinet for achy moments after a run or hike with the kids.

The only real downside to this oil is the potency — which comes in denominations of 1.5, 5, and 10 mg/mL. This is suitable for more minor symptoms, but may not be enough for people with heavy CBD demands.

  • Sourced from Colorado-grown organic hemp
  • Extracted with supercritical CO2
  • Tested for the cannabinoid content and purity in a third-party lab
  • Rock-solid 90-day return policy
  • Narrow product range
  • Low potency
  • They don’t ship to every state (i.e. Louisiana, Indiana, Arkansas, Kansas)

4. HempBombs

Technical Details
Total CBD Content 300 – 4000 mg
Available Flavors Unflavored, Acai Berry, Orange Creamsicle, Peppermint, Watermelon
Potency 10 – 133.3 mg/mL
What I Like About HempBombs:

I used HempBombs CBD isolate-based hemp oil for quite some time before switching to full-spectrum CBD oil and in my opinion, this is the best brand when it comes to CBD isolates. Their products contain 99% pure CBD and ZERO THC.

Now don’t get me wrong, CBD isolates are great, they offer consistent doses of CBD, contain 0% THC, and are generally cheaper than their full-spectrum counterparts. In most cases, I like using a full-spectrum extract like Royal CBD oil because of something called the entourage effect — which is a concept highlighting the phenomenon where cannabinoids like CBD tend to work better when other hemp-derived compounds are also present.

In isolates, the only cannabinoid present is CBD.

HempBombs CBD oil is available in five different strengths — from 300mg to 4000mg per bottle. The CBD is added in the form of a 99% pure isolate — which means there’s going to be virtually no traceable amounts of any other cannabinoids, including THC, CBC, CBG, or CBN.

You can also buy these oils in different flavors. Hemp Bombs often adds new flavors to the list, but my all-time personal favorite is the Acai berry. It’s not too sweet but adds a really pleasant flavor to the otherwise bland CBD and MCT oil formula.

  • Sourced from 100% certified organic hemp from European farms
  • Extracted with supercritical CO2
  • Completely THC-free
  • Tested in third-party laboratories for purity and potency
  • Available in 5 separate strengths
  • Up to 4000mg of CBD per bottle
  • Lacks the synergistic effects from other cannabinoids
  • The highest potencies are overkill for most users
  • Uses synthetic flavoring agents

5. CBDistillery

Technical Details
Total CBD Content 250 – 5000 mg
Available Flavors None
Potency 8.3 – 166 mg/mL
What I Like About CBDistillery:

CBDistillery is now one of the largest CBD companies in North America. The company began in 2016 as a legacy brand for Balanced Health Botanicals.

Over the years, CBDistillery has had the chance to really dial-in its CBD oil formula. The company now sells its CBD oil in two formats — “full-spectrum” and “THC-free.” The THC-free option is great for people who want to benefit from the synergy of CBD and other cannabinoids but without bringing any THC whatsoever into their system.

Even the full-spectrum option contains less than 0.3% THC — which is well below the amount needed to cause any psychoactive effects. These oils are both completely non-psychoactive.

You can choose between five different strengths, starting at 250mg up to 5000mg of CBD per bottle. This covers just about every range of potencies you would ever need. We recommend opting for the higher potency options because they have the best value overall. The higher potency you purchase, the further your dollar gets you.

The more potent options also las the longest because you need smaller amounts of the oil each time to get the desired dose of CBD.

I tried the 1000mg bottle to keep myself calm during the first few months after giving birth to my first son and I must admit it helped me maintain my sanity during that time. I found it to have a remarkable calming effect on the body and mind.

  • Available as full-spectrum CBD or pure CBD oil (THC-free)
  • 5 strengths to choose from
  • Carries up to 33.3 mg of CBD per mL (in the 1000 mg bottle)
  • Excellent value CBD oil
  • The hemp isn’t certified organic
  • No flavor options available
  • The company website is clunky and hard to navigate

6. NuLeaf Naturals

Technical Details
Total CBD Content 240 – 4850 mg
Available Flavors None
Potency 48.5 mg/mL
What I Like About NuLeaf Naturals

Nuleaf Naturals is one of the most popular CBD companies in the United States — most likely related to how long the company has been in the business of selling CBD. Nuleaf naturals were one of the first CBD companies to enter the mainstream market.

Despite the companies longstanding reputation, Nuleaf Naturals only sells one CBD oil. When you go to the website you’ll find a few different options, including a pet oil — but it’s important to understand that these are all the exact same full-spectrum extract, the only difference is the bottle sizes.

We love the simplicity of Nuleaf Naturals product lineup. The oils come with a decent potency of around 48 mg/mL, and just about every bottle size you can imagine. This makes it easy for everybody to find a product that works for them regardless of the budget.

With that said, if you have the cash, we highly recommend getting the larger bottle sizes in order to get the best value for your money.

You can choose between five different sizes:

  • Sourced from organic Colorado-grown hemp
  • Extracted using supercritical CO2
  • Made from a full-spectrum hemp extract
  • More expensive than the other brands in this ranking
  • Narrow product range

7. Charlotte’s Web

Technical Details
Total CBD Content 200 – 1800 mg
Available Flavors Mint Chocolate, Lemon Twist, Orange Blossom, Olive Oil
Potency 7 – 60 mg/mL

About Charlotte’s Web:

Charlotte’s Web is one of the pioneers in the American CBD industry. Established by the Stanley Brothers, the company has coined a reputation of a trustworthy manufacturer by helping now late Charlotte Figi with her treatment-resistant epilepsy. Although the company has recently received a warning letter from the FDA due to their health claims, they still have many faithful customers and a massive number of positive reviews on the web.

Charlotte’s Web CBD oil comes in several potencies: 200 mg, 500 mg, 1500 mg, and 1800 mg of CBD per bottle. The highest strength offers 60 mg of full-spectrum CBD per milliliter. There are two bottle sizes to choose from: 30 mL and 100 mL; Charlotte’s Web also has flavored variants of its CBD oil, including Lemon Twist, Orange Blossom, Mint Chocolate, and Olive Oil.

What could the company do better?

First off, they could change their extraction method because they use ethanol, which is less efficient than CO2 extraction. Secondly, and most importantly, the suspension in olive oil makes them taste a bit bitter — even in the flavored versions.

Pros:

  • One of the most reputable brands on the market
  • Full-spectrum CBD
  • Delicious flavored versions
  • Up to 1800 mg of CBD per bottle
  • Available in two sizes: 30 mL and 100 mL
  • Third-party tested for potency and purity

Cons:

  • Non-organic hemp
  • Ethanol extraction
  • Suspension in olive oil (bitter taste)
  • The company received a warning letter from the FDA in the past due to inappropriate health claims

8. cbdMD

Technical Details
Total CBD Content 300 – 7500 mg
Available Flavors Natural, Berry, Orange, Mint
Potency 10 – 250 mg/mL

About cbdMD:

cbdMD is another popular manufacturer that offers a wide range of CBD extracts, from tinctures to gummies to capsules, bath bombs, topicals, sleep aids, and pet products.

The brand offers a wide range of pure CBD oils, with up to 7500 mg of CBD per bottle. The highest potency comes with a whopping dose of 200 mg of pure CBD suspended in MCT oil for higher bioavailability and a smoother flavor. cbdMD also has three flavored CBD oils: Berry, Orange, and Mint.

Despite an impressive potency range, cbdMD uses broad-spectrum CBD in their products, which doesn’t evoke the full entourage effect. The higher potency may not necessarily mean better results in this case.

The company has high transparency standards; not only does cbdMD broadly describe their activity from farming to testing, but they also provide batch-specific certificates of analysis for their products, including the results for potency and common contaminants like pesticides, heavy metals, and residual solvents.

Pros:

  • US-grown, non-GMO hemp
  • CO2 extraction
  • THC-free
  • Up to 7500 mg of CBD per bottle
  • Batch-specific certificates of analysis

Cons:

  • Limited entourage effect due to the lack of THC
  • Most people don’t need such high doses of CBD in their routine

9. Medterra

Technical Details
Total CBD Content 500 – 3000 mg
Available Flavors Natural, Citrus, Mint Chocolate
Potency 16 – 100 mg/mL

About Medterra:

Medterra is a small craft company from California. The brand offers premium CBD oils in different spectra: full-spectrum CBD, broad-spectrum CBD, and isolates. The potency of these products ranges between 500 mg and 3000 mg of CBD per bottle, which is a standard range. On top of the unflavored version, there are two flavored options: Citrus and Chocolate

Medterra prides itself on making the real full-spectrum CBD because each bottle of its full-spectrum CBD oil comes with 2 mg of THC. However, these products are only legal in the states that have legalized higher amounts of THC for recreational use. So, if you want to buy the company’s products in all 50 states, your options are limited to broad-spectrum CBD and CBD isolate. These provide more CBD per bottle — upwards of 1000 mg.

The entire Medterra’s product range is tested in a third-party laboratory for their CBD content and safety.

Pros:

  • Premium-grade CBD oils
  • Up to 3000 mg of CBD per bottle
  • Available as full-spectrum CBD, broad-spectrum CBD, and isolates
  • Lab tested for potency and purity

Cons:

  • The “real” full-spectrum CBD oil isn’t available in all states
  • Some of the lab reports indicate higher CBD levels than stated on the bottle
  • No discounts for returning customers

10. Joy Organics

Technical Details
Total CBD Content 450 – 900 mg
Available Flavors Tranquil Mint, Fresh Lime, Summer Lemon
Potency 15 – 30 mg/mL

About Joy Organics:

Joy Organics holds the reputation of one of the most reputable CBD vendors in the industry. The company was established by a woman named Joy Smith, who has been using CBD oil to manage her problems with pain and sleep. After experiencing the benefits of CBD first-hand, she has decided to share her passion for cannabis with other health-conscious consumers.

See also  Cbd oil for ullrich dystrophy

The brand sells a range of broad-spectrum CBD products from certified organic hemp. They have many positive reviews all over the Internet; they also haven’t received any warning letter regarding health claims from the FDA — unlike many companies in this space (even the veterans like Charlotte’s Web).

The Joy Organics CBD oil features a broad-spectrum CBD formula in a modest potency range, from 450 to 900 mg of CBD per bottle. You can choose from three refreshing flavors: Summer Lemon, Fresh Lime, and Tranquil Mint. The strongest version of the Joy Organics CBD oil contains 30 mg of broad-spectrum CBD in every milliliter, which is a standard dose for most people who take CBD oil for daily supplementation.

In 2018, one of the company’s flavored CBD oils was found to contain a fungicide that is commonly sprayed on citrus fruit during independent lab testing. Fortunately, Joy Organics recalled the product shortly after this incident and implemented a new third-party testing system to make sure there are no flaws in the end product.

Pros:

  • Non-GMO, US-grown hemp
  • Supercritical CO2 extraction
  • Broad-spectrum CBD
  • THC-free
  • Delicious flavors

Cons:

  • A bit expensive
  • No high-strength oils

CBD Oil for Pain Management: Complete Guide for Beginners

Now that we’ve covered a few CBD oil options that are going to provide the best value for your money, let’s discuss how CBD is suggested to support chronic pain in the first place. We’ll also cover some of the most common ways people are using CBD oil for pain.

What is CBD Oil?

CBD stands for cannabidiol _ it’s one of the primary active ingredients in the cannabis plant. It’s completely non-psychoactive and offers a wide range of benefits to the human body.

CBD oil is a combination of a CBD extract, with a carrier oil to help dissolve and store the CBD. Most CBD oils use carrier oils like MCT oil, or hemp seed oil — which is then combined with CBD isolate, or full-spectrum hemp extract rich in CBD and other similar cannabinoids.

Cannabinoids like CBD are fat-soluble — which means they dissolve when mixed with oil, but won’t dissolve in water. By dissolving these compounds in an oil solution, the CBD becomes much easier to store and use. Instead of measuring out micrograms of CBD crystals or hemp resin, all you need to do is measure oil to get your dose of CBD. This can be done using a simple dropper that comes standard with most CBD oils.

Because of their ease of use, and long shelf-life, CBD oils have become the go-to method of using CBD and other hemp extracts.

You can also opt-out to use CBD-infused gummies if you wanted something discreetly, read our in-depth review on CBD Gummies to understand better.

How Does CBD Work?

Cannabis has been used for managing pain and inflammation for thousands of years.

The earliest records of the medical use of the herb date back to ancient China when the emperor Shen-Nung placed it among other therapeutic substances in the Chinese pharmacopeia (1). The leaves were wrapped around an injury as a poultice to reduce pain and discomfort, and reverse swelling and bruising.

Despite being a known medicine for a long time, scientists have only recently begun to unlock the mechanisms cannabis uses to achieve its important pain-killing benefits.

Since the discovery of the endocannabinoid system in 1992, CBD and other phytocannabinoids have been in the spotlight of modern medicine.

The endocannabinoid system is one of the most important neurochemical networks in the human body (2). It works by interacting with the endocannabinoid system — a series of hormones and receptors that help regulate over a dozen core processes in the human body. The active compounds in the cannabis plant are very similar to the naturally-produced hormones involved with our endocannabinoid system.

By interacting with the endocannabinoid system, CBD and other cannabinoids are able to modulate several key processes, such as:

  • Appetite
  • Immune function
  • Memory
  • Mood
  • Stress
  • Sensory perception (including pain)
  • Inflammation
  • Reproductive health
  • Nerve function
  • Sleep

How Can CBD Reduce Pain Transmission?

How does all of this relate to pain? The answer lies in the way pain is transmitted to the brain.

When we injure ourselves, cells in the immediate vicinity begin releasing compounds that trigger a cascade of inflammation and sensory activation — which is what triggers the pain transmission.

The pain signal is then sent to the spinal cord through a network of nerves distributed all around the body.

Once in the spine, the pain signal is sent through a gateway (opioid and vanilloid receptors) designed to limit the amount of signal that ends up in the brain for processing. This works like a border crossing. The border security decides whether or not you’re allowed to enter and what you can take with you.

In the context of pain, these gateways can limit the amount of pain signal that continues across the border to the brain. If more pain signal is allowed to pass, the brain perceives more pain. If the pain is stopped at the border, the brain perceives less pain.

Conventional pain medications work by activating the opioid receptors acting as a key gateway for pain transmission to the brain.

CBD has a similar effect, but through a different receptor is known as the vanilloid receptors. These vanilloid receptors are tasked with regulating a specific form of pain caused by either heat or inflammation. CBD has been reported to modulate this vanilloid receptor — leading to a reduction in the pain signals sent to the brain from inflammatory causes such as arthritis, muscle damage, or infection, to name a few.

CBD has other ways it can limit pain transmission as well:

  • CBD may reduce inflammation, limiting the initial cause of pain in the body
  • CBD acts as an antioxidant, helping the body resist and recover from damage
  • CBD relaxes muscle fibers, reducing pain caused by muscle spasms and tightness

More research is needed to fully understand how CBD and other active cannabinoids can block pain. Every year dozens of new research papers are published in an attempt to paint a clear picture of how CBD works, how to get the most benefit from the supplement, and what its limitations are.

(Pain Transmission Pathway to the Brain)

Choosing CBD Oil Companies: How to Differentiate the Good From the Bad

CBD has become a lucrative business. Companies are selling a myriad of different CBD oils and other products in an attempt to cash in on the new health trend. This means there are a lot of excellent products coming to market, but it also means there’s a lot of trash as well. It’s important as a CBD user that you understand what makes a CBD oil good, and what makes it bad so you can avoid wasting your money, or worse — using CBD oils that contain harmful or damaging ingredients.

Let’s cover the most important points to remember when shopping for CBD oil online or in-store.

1. Check the Hemp Source

The source of the hemp used to make the oil is vitally important when it comes to determining which CBD oils are the best. The main reason comes down to the botany of the hemp plant itself.

Hemp is a bio-accumulator — which means it has the tendency to absorb compounds from the soil and accumulate them in its leaves, stems, and roots. The deep taproots of the hemp plant stretch far beneath the soil, pulling out and storing all the heavy metals and other elements it can find in the soil.

This aspect is in part why hemp is so nutritious, but it also means that plants grown in contaminated soils often contain contaminants that can be harmful to your health. Some of the worst offenders are heavy metals — which can build up in the body over time and lead to severe long-term health effects.

You want to avoid consuming heavy metals at all costs.

Poorly grown hemp could contain heavy metals, as well as other contaminants like mycotoxins, or pesticide residues that will end up in the CBD oil after all the processing is complete.

For this reason, it’s important to purchase CBD oil from companies that account for this effect. Only buy from company’s that make an effort to source hemp from organic farms, and take measures to assess every batch of hemp that enters the facility to determine heavy metal, microbial contaminant, and pesticide contamination.

The best hemp sources tend to come from states like Oregon, Colorado, or Alabama, as well as neighboring countries like Canada or Scandinavian countries. These places are all known for having high standards for hemp cultivation, and clean soils.

2. Look for CO2 Extracted Products

Once the company has the hemp, they need to extract the CBD from it. You can do this in many different ways using solvents like ethanol, methanol, hexane, ether, or butane. All of these solvents work to strip the active compounds from the hemp plant and can then be evaporated to leave behind a pure CBD-rich resin.

however, there’s a problem with these solvents.

Even in professional lab settings, it can be very difficult to remove all traces of these solvents from the final product. Most of these solvents are toxic to the human body, even in trace amounts.

Therefore, the best companies are using another method to strop the active ingredients from the starting hemp material. This method uses CO2 placed under high pressure. the high pressure and temperature control convert the CO2 into a phase that’s neither liquid nor gas. This special state is referred to as being supercritical.

Supercritical CO2 acts just like any other solvent, but with one key benefit — as soon as the pressure is relieved, the gas evaporates completely, leaving behind no harmful chemical residues.

when shopping for CBD oil, it’s ideal to look for a company that uses supercritical CO2 to extract the CBD rather than the toxic solvents mentioned above. Supercritical CO2 is very expensive and highly technical — but usually produces a far superior product in the end.

If a company is using harsh solvents like butane or propane (or they don’t tell you anything about their extraction methods), it’s a sign that you should look for another brand.

3. Ask for Third-Party Lab Reports

Every company has the option to send their products to an independent lab or third-party testing.

These laboratory tests check for the entire cannabinoid profile of the extract and are able to detect over 200 common contaminants.

Before a CBD product becomes available for sale, it should pass the laboratory test for potency and purity. If any inconsistencies are shown between different batches of the same product, the company should rework it and send it for analysis once again.

High-quality CBD companies will continually send each batch of product to a lab with no affiliation to the company (called a third-party or independent lab) for testing. These results are then published publicly on the website for customers to view.

The best companies will take this even one step further — adding a database and batch numbers on every bottle of CBD oil so you can view the results for your specific bottle of oil. Third-party testing is now an industry standard.

Always buy your CBD oil from companies that show third-party lab reports on their website. Only then will you know what’s inside the bottle before you even order a product. If the company is producing CBD oil that’s as high quality, as they say, there should be nothing to hide in these lab tests and they should be listed publicly on the company website. If you can’t find them on the site, you can ask customer service for these as well.

If these tests don’t exist, or you can’t track them down from the website or customer service — it’s best to avoid this company and move on to another that takes this important step seriously.

What the Research Says About Using CBD Oil for Pain:

Understanding how CBD works is no simple task. This compound is incredibly complex — working through a number of unrelated receptors around the body, interacting with enzymes, cell membranes, and various other cell structures. This makes studying CBD very difficult.

Nevertheless, there have been thousands of research papers published on medical marijuana — seeking to understand the interaction between cannabinoids like CBD and the human body. A lot of this research specifically focused on the effects of CBD on various forms and causes of pain. Let’s explore some of the results this research has yielded in the context of pain management.

1. CBD Oil for Chronic Back & Nerve Pain

The painkilling properties of cannabidiol have been most thoroughly studied in animal models, as well as a handful of human clinical trials.

One of the best studies we have available on the topic is a meta-analysis published in 2017. This analysis looked at 24 different clinical trials involving 1,334 patients over several years and demographics. These studies all used various forms of cannabis for treating chronic pain. The analysis reports that many of these studies showed a reduction in chronic pain scores by 50% or more (3) — suggesting the cannabis plant to be a potential treatment for chronic pain.

Another clinical trial looked at the effects of a combination of CBD to THC in the treatment of intractable cancer pain. This study found that twice as many people in the treatment group given CBD and THC had a 30% or more reduction in pain symptoms at the conclusion of the trial (6).

Even though more clinical trials on humans are needed to gauge how CBD affects specific forms of pain or other conditions, scientists believe the efficacy of CBD in treating chronic pain is related to its anti-inflammatory effects (3).

2. CBD Oil for Arthritis

CBD has had a lot of research as a potential alternative to prescription and non-prescription pain medications commonly used for alleviating arthritis pain.

Researchers have found a clear link between the endocannabinoid system and the pathophysiology of osteoarthritis, which is a degenerative joint disease associated with chronic pain and inflammation (4).

One of the key areas CBD is thought to support osteoarthritis specifically is through the effects on an enzyme known as 5-lipoxygenase — AKA 5-LOX. CBD has been shown to inhibit this enzyme (7), which converts fatty acids into pro-inflammatory compounds. These inflammatory messengers have been shown to be a key component in the underlying inflammation involved with osteoarthritis (8).

By reducing the underlying causes of arthritis pain, CBD is thought to reduce the overall burden of pain from the condition over the long term.

3. CBD and Multiple Sclerosis (MS) Pain

Due to its antioxidant and anti-inflammatory properties, CBD is a potent neuroprotective — which is how experts believe CBD is able to relieve debilitating MS pain, —which affects roughly 50–70% of patients diagnosed with the condition.

A study conducted on animals at Cajan Institute tested the anti-inflammatory effects of CBD on mice the researchers wanted to find out if CBD can provide a reversed inflammatory response on those cells. After ten days, the researchers found a reduction in inflammatory markers with a rodent encephalitis model designed to imitate the impact MS has on the body (5).

More research is needed to see exactly how these effects are translated to humans. Currently, there are 23 clinical trials currently underway, or planned within the next 12 months seeking to explore the effects of CBD on MS.

4. CBD Oil in Sports: Injuries & Muscle Endurance

Cannabidiol can be applied in two different ways when it comes to pain and physical activities. For example, when you administer CBD orally in the form of oil as a post-workout, it helps alleviate the muscle inflammation that troubles athletes once they go beyond the edge again.

If, however, you’re suffering from an injury, it’s best to apply CBD topically. Its anti-inflammatory and neuroprotective properties allow the cannabinoid to relieve pain and improve regeneration capacities.

Does CBD Have Any Side Effects?

The main reason why parents are so enthusiastic about CBD is that this cannabinoid is completely non-intoxicating, doesn’t cause addiction, and has only a few mild side effects when taken at excessive doses.

Research shows that even doses up to one and a half grams have no severe side effects on human health (9).

Despite being a notoriously safe supplement, there are some side effects of using CBD in high doses. Let’s cover the most common side effects people report from using CBD:

  • Anxiety
  • Brain fog
  • Reduced appetite
  • Mood changes
  • Diarrhea or constipation
  • Dizziness or lightheadedness
  • Drowsiness or fatigue
  • Dry mouth
  • Nausea and vomiting

The most common side effect by far, like other forms of cannabis, is dry mouth. This is best managed by taking your CBD oil along with some juice like pineapple or orange juice.

Another common side effect is lowered blood pressure, which may trigger another unwanted reaction — lightheadedness. This side effect is important to consider if you suffer from low blood pressure already or are taking blood pressure-lowering medications.

Always consult your doctor before using CBD or other cannabis extracts if you’re taking prescription medications or have underlying medical conditions.

In Summary: Buying CBD Oil For Pain

As CBD becomes more popular around the world, scientists are publishing new research on cannabinoids on a near-weekly basis. As time goes on, experts are mapping out the complicated mechanisms CBD and other hemp derivatives are using to support both acute and chronic pain of all different origins.

Here are the main takeaways from the current research:

  • CBD inhibits inflammation at several different levels
  • CBD offers antioxidant support
  • CBD may relieve muscle tension and inflammation
  • CBD interacts with the vanilloid receptors in the brain responsible for regulating inflammatory pain transmission

When it comes to pain, CBD appears to target the cause of the problem instead of just masking its symptoms.

Getting relief on so many levels and without any harmful side effects or risk of addiction is the reason why CBD oil has become so popular over the past half a decade.

I hope this guide has managed to clear up any confusion regarding CBD oil and pain, and given you the insight necessary to find the right CBD oil for the job.

Have you tried CBD oil for chronic pain? Did you feel any difference? Let me know in the comments below!

References:

  1. Brand, E. J., & Zhao, Z. (2017). Cannabis in Chinese Medicine: Are Some Traditional Indications Referenced in Ancient Literature Related to Cannabinoids?. Frontiers in pharmacology, 8, 108.
  2. Alger B. E. (2013). Getting high on the endocannabinoid system. Cerebrum: the Dana forum on brain science, 2013, 14.
  3. Aviram, J., Samuelly-Leichtag, G. (2017) Efficacy of Cannabis-Based Medicines for Pain Management: A Systematic Review and Meta-Analysis of Randomized Controlled Trials. Pain Physician, 20(6), E755-E796.
  4. Bruni, N., Della Pepa, C., Oliaro-Bosso, S., Pessione, E., Gastaldi, D., & Dosio, F. (2018). Cannabinoid Delivery Systems for Pain and Inflammation Treatment. Molecules (Basel, Switzerland), 23(10), 2478.
  5. Elliott, D. M., Singh, N., Nagarkatti, M., & Nagarkatti, P. S. (2018). Cannabidiol Attenuates Experimental Autoimmune Encephalomyelitis Model of Multiple Sclerosis Through Induction of Myeloid-Derived Suppressor Cells. Frontiers in immunology, 9, 1782.
  6. Johnson, J. R., Burnell-Nugent, M., Lossignol, D., Ganae-Motan, E. D., Potts, R., & Fallon, M. T. (2010). Multicenter, double-blind, randomized, placebo-controlled, parallel-group study of the efficacy, safety, and tolerability of THC: CBD extract and THC extract in patients with intractable cancer-related pain. Journal of pain and symptom management, 39(2), 167-179.
  7. Takeda, S., Usami, N., Yamamoto, I., & Watanabe, K. (2009). Cannabidiol-2′, 6′-dimethyl ether, a cannabidiol derivative, is a highly potent and selective 15-lipoxygenase inhibitor. Drug Metabolism and Disposition.
  8. Lascelles, B. D. X., King, S., Roe, S., Marcellin‐Little, D. J., & Jones, S. (2009). Expression and activity of COX‐1 and 2 and 5‐LOX in joint tissues from dogs with naturally occurring coxofemoral joint osteoarthritis. Journal of orthopaedic research, 27(9), 1204-1208.Chicago
Nina Julia

Nina created CFAH.org following the birth of her second child. She was a science and math teacher for 6 years prior to becoming a parent — teaching in schools in White Plains, New York and later in Paterson, New Jersey.

Leave a comment Cancel reply

Your email address will not be published. Required fields are marked *

Save my name, email, and website in this browser for the next time I comment.