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Best CBD Oil 2022 | Top 5 Brands For Pain, Anxiety & Stress

Looking for the best CBD oil in 2022? With hundreds of brands trying to entice you into buying their CBD products, it can be tricky when it comes to buying safe and effective CBD oil online. How do you find the top CBD companies? In this 2022 updated buyer’s guide, we’ve put together a list of the 5 best CBD oil brands on the market today.

Our CBD oil recommendations and comparisons below are based on extensive product research, analysis, and verified customer experiences. We will never recommend a product we haven’t personally tested.

The 5 best CBD oils in 2022

*A quick note before you read our CBD oil reviews below: Quitnet was not paid to include any of the above CBD companies on our list. However, we may receive a small commission from some of these brands if you click through and decide to purchase (at no additional charge to you). We promise and assure you that these CBD products are the best you can buy in 2022, and we 100% stand behind them. To see the best CBD oils in the UK, click here.

How did we decide?

24 CBD oils considered — 100+ hours of research — 3 health experts consulted

When determining the most effective CBD products on the market, we looked at several key categories. Our team looked into the potency of the CBD oil (how strong each dose is), the flavor of the CBD, ingredient transparency, affordability, shipping options, and customer service.

Best CBD oil: extended reviews

1. cbdMD

cbdMD’s CBD oil is considered great for quality, affordable health, and wellness products made from CBD-rich hemp. This unique company is dedicated to providing you with the highest quality, most affordable hemp CBD oil on the market.

In fact, as far as we are aware, cbdMD produces one of the most effective CBD tinctures at the lowest prices. Their 300mg broad-spectrum CBD oil drops begin at just $29.99 – and if you use our exclusive coupon code you’ll receive a further saving.

People only seem to have good things to say about cbdMD, probably because of their distinctive extraction process. They use CO2 to extract the CBD which produces an oil that is 99% pure. Their cannabinoid extract also contains CBG, CBDV, and other beneficial molecules, essential oils, terpenes, and amino acids. This allows you to achieve the highly sought after “entourage effect”, which is the result of all the valuable cannabinoids in the CBD oil working together to provide you with natural relief.

If you still need help deciding, read our in-depth cbdMD review.

Key features of cbdMD:

  • The best prices in the CBD industry
  • Best and cheapest CBD oil
  • Reliable and friendly customer support
  • 30-day no questions asked money-back guarantee
  • 100% organic, USA-grown, non-GMO and gluten-free
  • Non-psychoactive (zero THC)
  • Tested to guarantee a safe and potent product
  • Free delivery on all orders (no minimum order size!)

cbdMD’s CBD oils range in price from $29.99-$149.99, depending on the potency.

2. CBD Pure

Trusted not only by health-conscious people but also by holistic health professionals, CBDPure hemp oil manufactures one of the best pain-relieving CBD oils available today. CBDPure hemp oil uses the purest, highest quality CBD ingredients backed by wisdom and principles.

They even offer a massive 90-day money-back guarantee on all their products. If you buy from CBD Pure and don’t quite experience the results you were expecting, you can request a full refund on your order. We think this says a lot about their confidence in their products. No other CBD brand offers a money-back guarantee for 90 days.

CBDPure hemp grown oils are carefully grown in Colorado and are 100% free of all synthetic or artificial ingredients. They also test every batch of oil to ensure that it meets the purity standards their company demands. CBDPure uses terpene analysis to provide an optimized industrial hemp oil that maximizes the therapeutic effects of CBD.

Although they are a rather small company, they have impeccable customer service. If you have any concerns or general questions about their CBD oils, you can be sure to get in contact with their team. CBDPure believes that they deliver health benefits that no other legally grown hemp product can. Some of their customers choose their outstanding CBD oils to manage chronic health and pain problems, and others use CBD supplements daily to improve their mood, stress levels, and overall health and well-being.

In an industry with hundreds of overpriced and low-quality products that don’t work, CBD Pure really stands out for their premium quality and simplicity.

If you still need help deciding, read our in-depth CBDPure review.

Some of the CBD oils they currently offer are:

  • 100 mg CBD oil extract
  • 300 mg CBD oil extract
  • 600 mg CBD oil extract

Key features of CBDPure:

  • 90-day money-back guarantee
  • Best CBD for pain, anxiety, and sleep
  • Strongest CBD oil tinctures available
  • Uses a chemical-free CO2 extraction process
  • Third party tested for Cannabinoid Profiling, Microbiological Screening, Pesticide Testing, Residual Solvent Testing, and Terpene Analysis

CBDPure’s CBD oils range in price from $29.99 to $79.99.

3. Green Roads CBD

Green Roads prides itself on taking full advantage of nature’s perfect remedies – something they do very well. In fact, Green Roads is one of the most experienced manufacturers and distributors. They are committed to improving lives, inspiring hope, and restoring happiness.

All of the Green Roads CBD oils are safe and extremely effective. They use natural ingredients, and their broad spectrum cannabidiol CBD oil is packed with nutrients from the raw hemp plant. Green Road’s precisely formulated combinations of cannabinoids immediately respond to pain.

Their 350 mg CBD is the original broad-spectrum oil (THC-free) that started it all for this company. Green Road’s oil is infused with the highest quality pharmaceutical quality naturally occurring cannabidiol. It is a vegetable glycerin based olive oil that is vapeable and sublingual. This powerful oil is American made by an experienced licensed pharmacist. It is a quality you can trust.

More and more people have trusted this powerful CBD oil to relieve their suffering from depression, pain, inability to focus, anxiety, addiction, stress, epilepsy and to sleep better.

If you still need help deciding, read our in-depth Green Roads CBD review.

Key features of Green Roads CBD:

  • Good CBD oil solution for pain relief
  • Extremely potent
  • Synthesized by an experienced pharmacist
  • High CBD concentration (even in their gummies)
  • Pharmaceutical grade
  • Affordable CBD oil
  • Can be consumed through oral use or by vaping
  • One of the cleanest and purest CBD oils available
  • THC is removed entirely in the extraction process, leaving 100% pure, natural CBD
  • Will last up to 6 to 8 months after the purchase date
  • Free shipping available with all orders

Green Road’s CBD oils range in price from $26-$64.

4. Charlotte’s Web

Charlotte’s Web is known to be a miracle strain with a potent CBD concentration. The Charlotte’s Web cannabis breed was inspired by Charlotte Figi. Charlotte’s Web has a unique story. Charlotte lived with Dravet syndrome (a rare type of epilepsy) and experienced numerous seizures every day (10). Her story inspired the owners of the company to develop this incredible strain. Charlotte’s Web is now produced in a wide variety of products.

Charlotte’s Web is a family owned company (the well-known Stanley Brothers) and the exclusive provider of the Charlotte’s Web strain (11). They claim to produce the world’s most trusted hemp extract. Charlotte’s Web is a company focused on quality, safety, consistency, and social responsibility to support thousands of lives. Every step of the process in producing Charlotte’s Web is overseen – from seed to shelf – to ensure the highest quality.

If you still need help deciding, read our in-depth Charlotte’s Web CBD review.

Key features of Charlotte’s Web CBD:

  • CW Hemp Extract incorporates several cannabinoids, including CBN, CBG, CBC, Phytonutrients, Terpenes and Amino Acids found in their proprietary cannabis strains as well as a whopping 500 mg of CBD in each bottle
  • The extract comes from top-quality hemp which is naturally rich in CBD
  • Trusted company and family owned
  • MCT oil/hemp seed oil used as carrier
  • USA Grown

Charlotte’s Web CBD oils range in price from $39.99-$299.96.

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5. CBDistillery

A trusted company — CBDistillery is a completely transparent company with nothing to hide about their products or processes. They are known to be some of the most knowledgeable, passionate, and honest people in the industry.

CBDistillery provides a maximum CBD potency in their oil. They produce a first-class CBD isolate that is 99% pure and is available in a range of tinctures used to help treat everything from chronic pain and anxiety to sleep disorders.

You can always be prepared when you need it the most with CBDistillery’s 30 ml bottle of powerful CBD tincture. This bottle is twice the size of most others and packs twice the punch. Their CBD oil is excellent value if you want to keep something extra on hand for fast relief. It is also one of the most potent, finest CBD oils on the market. At 5000 mg this 30 ml full-spectrum CBD oil tincture is ready when you need another dose fast.

If you still need help deciding, read our in-depth CBDistillery review.

Key features of CBDistillery:

  • Pure oil
  • 100% all-natural (unflavoured) CBD oil
  • 3rd party lab-tested
  • Easy to absorb
  • Fast-acting CBD

CBDistillery’s CBD oils range in price from $19-$240.

Compare our top-rated CBD brands

Brand Popular Product Lowest Price Size CBD (mg)
1. cbdMD CBD Oil Tincture Drops $29.99 30ml 300-7500
2. CBD Pure CBD Hemp Oil $29.99 60ml 100-750
3. Green Roads CBD CBD Oil $26.99 30ml 100-3500
4. Charlotte’s Web Full Strength CBD Oil $39.99 30ml 300-3000
5. CBDistillery Full Spectrum CBD Oil $19 30ml 200-2500

CBD oil for anxiety

CBD oil is most commonly known for being a holistic approach to alleviating some symptoms of anxiety, but without the nasty side effects often experienced with anxiety medications.

How does CBD oil achieve this? It works by signaling the serotonin receptors in your brain. These receptors are responsible for your calmness and happiness levels. Multiple researchers at clinical institutions have found that CBD (or hemp oil) is effective when it comes to reducing anxiety amongst users and helps them to feel more relaxed and calmer during their day.

However, it’s important to consider a few things when finding the right CBD oil for anxiety. The best CBD oils that help with anxiety are usually high in potency and only contain natural, organic ingredients. Remember to stay clear of products that contain artificial sweeteners.

CBD oil comes in a variety of strengths, so it’s important to pick a suitable strength to help with your anxiety. The CBD oil produced by cbdMD is our preferred solution for reducing and relieving anxiety symptoms. Their high-quality products are made using natural ingredients (sourced from organic hemp) and they even provide a 30-day money-back guarantee, so you have nothing to lose.

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CBD oil for insomnia

Finding it hard to sleep at night? CBD oil might be a great option for you to consider. Sleepless nights can result in long and bad-tempered days, which can often leave you in a bad mood and feeling unrest.

In the past, the common way to treat your insomnia would be to use sleeping pills. Although pills may be effective to an extent, CBD oil is now proving to be a much better, safer, and natural way to fall asleep easily, making it one of the best solutions for insomnia.

THC in cannabis is known to block you from achieving deep REM sleep. REM sleep is essential for feeling rested and relaxed the following day. On the other hand, CBD works by calming the nervous system, which can instead prompt deeper REM sleep.

If you’re looking for a CBD oil solution to help with getting to sleep easily, it’s best to pick a product that doesn’t contain any THC. This ensures your REM cycle isn’t disrupted, allowing you to get a good night’s sleep.

We recommend using CBDPure’s CBD oil for insomnia, as it comes packed with all the beneficial cannabinoids. The oil comes in various strengths (from 100mg to 750mg), and prices are fairly affordable.

CBD oil for pain

Anyone currently suffering from chronic plan knows that it’s unpleasant. Finding the best products to reduce painful symptoms can make all the difference between enjoying a wonderful day and not being physically able to do anything.

CBD oil is generally considered to be a safer alternative to traditional pain relief medications. Many research studies indicate that CBD oil is helpful for alleviating painful symptoms of arthritis, joint pain, muscle spasms, and other pain-related issues.

A study carried out by the US National Library of Medicine found that patients who were being treated for chronic pain reported that cannabis and CBD products produced the same, beneficial results as prescription pain medication, but without any of the undesirable side effects of opiates.

In fact, another case study carried out by the Hadassah Medical School in Israel found that full spectrum CBD oil contains significantly higher CBD amounts compared to other extraction processes. If you’re looking to treat inflammation and pain, the most effective option is to use a full spectrum product.

If you’re looking for a reliable CBD oil to specifically reduce pain, we recommend cbdMD. They use a full spectrum extract (which includes traces of additional cannabinoids), which allows them to create a highly potent oil that is efficient at alleviating pain.

Takeaway

The CBD industry is overwhelmed with incredible options to help treat issues ranging from stress to inflammation to chronic pain. Each one of these companies takes great pride in what they do and strives to offer only the best quality CBD products.

While every one of the CBD oils on our Top 5 list is full of benefits, it is essential to find the one that is best for you. Whether you need to relax or find relief, the perfect solution is out there and probably on this list. What qualities make sense for you and what you’re dealing with?

These companies are investing in top researchers, pharmacists, farmers, laboratories, tests, and technology – fighting to give you the quality of life you deserve. It’s a great time to take advantage of all CBD has to offer.

Frequently asked questions

Q: What is CBD oil?

People with chronic pain, depression, anxiety, epilepsy, and other health issues look to CBD oil for relief. Many even consider CBD oil a miracle product. We agree. There aren’t many alternative treatments available that have shown themselves to be as versatile and effective as CBD.

But what is CBD oil exactly? CBD oil stands for cannabidiol oil. Cannabidiol is one of the 90+ cannabinoids found in cannabis. A Harvard chemist named Roger Adams discovered CBD by accident in 1940. Six years later, he started using it in animal/clinical trials and was shocked when he discovered that CBD doesn’t have any adverse mental effects.

Unlike medical marijuana, pure CBD oil does not contain THC; the psychoactive compound commonly known to cause a “high” feeling. Because of this, it has become legal to use throughout the U.S. CBD oil has allowed countless people to finally get the relief and treatment they need, but without the adverse effects of marijuana.

With so many new CBD products on the market, it can be overwhelming to figure out what oil is best for you. The Quitnet team lives and breathes CBD oil – we’ve tested and researched numerous CBD oil products so you don’t have to. Our goal is to help you learn all you can about CBD so you can make the smart decision on which CBD oil to buy.

Q: What is CBD oil used for?

Since it first gained recognition as a potential treatment for epilepsy back in 1980, the uses of CBD oil have expanded dramatically. Nowadays CBD is known to treat countless physical and mental conditions. For some, CBD oil has even replaced traditional medicine. Let’s look at some of the many ways the top CBD oils can help you.

Pain Relief

Chronic pain management is arguably the most common use for CBD oil. Studies suggest that CBD can have an even better pain-relieving effect than opioid-based medications, but without the risk of dependence, overdose, and other serious side effects.

The FDA (Food Drug Administration) has not yet approved CBD for any medical conditions (CBD is not intended to diagnose or prevent any disease). But even without the Food and Drug Administration (FDA) approval, CBD oil has gained a massive amount of supporters because of how useful it is for pain relief (1).

Depression

We know that depression can be crippling to even the best of us. Unfortunately, many anti-depressants can come with a plethora of side effects. CBD is often used as an alternative.

Studies show that CBD has an anti-depressant effect. While there is not currently any testing done on humans, many CBD oil users have found it to help manage depression. This is likely because CBD has the ability to influence the serotonin receptors in our brain/endocannabinoid system (2).

Anxiety

Social anxiety disorder (SAD) is one of the most common disorders that go unnoticed and undiagnosed. CBD has been shown to have an anxiolytic-like effect; it reduces general anxiety (3).

One double-blind, randomized study put participants in a simulated public speaking test and the results showed that CBD significantly reduced anxiety, discomfort in speech, and cognitive impairment.

More and more people are looking to CBD for anxiety relief.

Sleep Disorders

There are two reasons CBD oil is perfect for those who have sleep disorders. First, CBD has a calming effect on the brain. We all know what it’s like to not be able to relax before bed fully. CBD can help calm our bodies and our minds.

Second, as we talked about before, CBD relieves pain. We know that even mild pain can contribute to sleep disorders. Eliminating that pain can make all the difference. This is why there is an increasingly large number of people now switching to quality CBD oil for sleep.

Nausea

Another frequent use for CBD oil is reducing nausea, which can be caused by a wide range of conditions. A study suggests that CBD has a general nausea-suppressing effect.

This is very good news for cancer patients because chemotherapy often causes nausea, amongst many other side effects. One study on chemo patients concludes that CBD helps ease nausea and increases the quality of life (4).

Neurological Disorders (Seizures, etc)

One of the most incredible things about CBD oil is its ability to prevent and stop seizures. Frequent seizures can certainly make life more than a little difficult. Many people with epilepsy have turned to CBD oils. Remember again, CBD is not guaranteed to cure or prevent all health issues, but it has certainly been proven time and time again to provide wonderful benefits.

Studies show that CBD can significantly reduce the number of seizures or even completely stop patients from having seizures altogether; often in children who were unresponsive to other medications (5).

Q: How is CBD oil produced?

The production of CBD oil can vary slightly depending on the manufacturer. To create their CBD products, CBD producers choose a cannabis plant that is naturally high in CBD. This ensures high quality and a high yield. Many manufacturers create a specialized strain of cannabis, so they get the greatest amount of CBD per plant.

In some cases, the whole plant is used; other times, only a certain part of the plant is used. Most cannabis specialists prefer to use the entire plant to get a broad spectrum of cannabinoids. It is then cultivated and readied for the CBD extraction.

Next, the plant is soaked in alcohol; the ethanol removes the cannabinoids from the plant. The ethanol solution is then heated up to cause it to evaporate. What is left behind is pure CBD oil.

There’s another way to extract CBD. It is called CO2 extraction. CO2 is forced through the plant to extract the oil.

Once the oil is extracted, many producers add flavoring since the oil does not taste too pleasant on its own.

Q: Is CBD legal?

The answer to this question is too complicated for us to give you a straight yes or no. In all 50 states, CBD is considered legal. However, it’s not quite that simple. What specific type of CBD is considered legal and illegal can vary from state to state. The main factor to consider is whether or not the CBD oil is derived from hemp or marijuana.

Marijuana and hemp indeed both come from the cannabis family. The difference between the two is their chemical makeup, particularly their levels of psychoactive THC. Hemp does not contain a level of THC higher than 0.3%, while marijuana can have a THC level of up to 30%. The very low percentage of THC in hemp will be nearly impossible to get high off of, while the 30% level of THC in marijuana will definitely make you high.

The law doesn’t have a problem with CBD oil made from hemp. However, in many states, law enforcement does have a problem with CBD oil made from marijuana.

Both hemp and marijuana-derived CBD oil are legal for medical use in 29 states: Alaska, Arizona, Arkansas, California, Colorado, Connecticut, Delaware, Florida, Hawaii, Illinois, Maine, Maryland, Massachusetts, Michigan, Minnesota, Montana, Nevada, New Hampshire, New Jersey, New Mexico, New York, North Dakota, Ohio, Oregon, Pennsylvania, Rhode Island, Vermont, Washington, and West Virginia. However, laws on CBD are regularly changing so check with your state.

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There are currently four states where CBD oil extracted from marijuana is completely illegal: Idaho, Kansas, Nebraska and South Dakota.

In eight states – Alaska, California, Colorado, Maine, Massachusetts, Nevada, Oregon, and Washington – both hemp and marijuana CBD oils are legal for medical and recreational use. If you happen to live in one of these states, you lucked out.

Again, laws change so check and make sure you can legally own and use CBD oil. We at Quitnet are not lawyers. So it is best to consult a professional before you purchase any CBD oil to ensure you don’t break any laws.

Every day the world is becoming more and more aware of the amazing benefits of CBD oil, and we are continuously moving towards legalization.

Q: When do CBD effects kick in?

The amount of time it takes for CBD to affect the human body depends on the strength of the oil, how you use it, and how much of it you use. There are four primary ways you can use CBD oil: using a vaporizer, applying underneath the tongue (sublingual), rubbing it into your skin (topical), and digesting it (through CBD edibles or capsules).

The quickest way to get CBD into your system is by turning it into a vapor. This is done by using vape pens. The second fastest way is to drip the oil underneath your tongue. This can take between 20-40 minutes to take effect. The third way to use CBD oil is to rub it into your skin. This is best when you apply it to an area on your body that is causing you pain. However, it can take an hour for CBD oil to start working using this method. And finally, digesting CBD through edibles or capsules can take between 20 minutes and two hours to take effect. Consuming CBD in this way is recommended on an empty stomach. This will help it get into the bloodstream quicker.

Q: CBD vs THC – what’s the difference?

There are more than 100 known cannabinoids found in cannabis. CBD and THC are the most abundant—and the most studied—cannabinoids. Both of these interact with the endocannabinoid system. However, they each can have very different natural effects.

The most obvious difference between CBD and THC is that one of them causes a “high” when consumed. THC is the psychoactive element in marijuana that produces a high. It has this effect because it is a direct agonist of the CB1 receptors in the endocannabinoid system.

On the other hand, CBD does not bind with the CB1 receptors. Instead, it is considered an antagonist of CB1 agonists. This means that it not only cannot cause a high, but it also suppresses the THC’s ability to activate CB1 receptors.

The key difference between hemp and marijuana plants is how much CBD and THC they contain. Hemp contains less than 0.03% THC, while marijuana can contain up to 30% THC.

The high amounts of THC in marijuana is what makes it illegal in many states. Oil made from hemp is legal in most states while oil made from marijuana is illegal in some states. THC and marijuana are listed in the U.S. Controlled Substances Act and therefore prohibited under federal law.

THC is known to have other specific characteristics:

  • Red eyes
  • Dry mouth
  • Lowered reaction times
  • Memory impairment
  • Increased heart rate
  • Impaired coordination

However, there are no reported cases of a fatal marijuana overdose, and this is not likely to ever happen. But THC can be harmful. Studies suggest that strains high in THC can have long-term psychiatric effects in adolescents including an increased risk of schizophrenia.

CBD is considered safe in large doses, with no known long-term effects. Even chronic usage of CBD has shown no adverse psychiatric, neurological, or clinical effects.

Q: Do you need a doctor’s prescription?

The short answer is no, you do not need a prescription for CBD oil. No prescription or doctor is needed to purchase any CBD products that do not contain THC. THC is the psychoactive compound in marijuana. However, CBD oil is derived from the hemp plant which contains minuscule amounts of THC (less than 0.3%). Some states legalized the purchase and use of CBD oil containing THC and in those states, you are not required to have a doctor’s prescription.

While the fact that you don’t need a prescription to purchase CBD oil is a good thing, it can also be a negative thing; if your insurance covers prescription medications, you will not be able to have your insurance cover CBD oil since it is not a prescription medication.

To summarize, CBD oil derived from hemp (containing less than 0.3% THC) is legal in all states. You can simply purchase it without a prescription online or in store. Laws and regulations differ from state to state on THC, so check with a law professional.

Even though you are not required to have a prescription for CBD oil, we recommend that you consult your doctor before using any new treatment. Your doctor may be able to recommend just the right amount of CBD oil for your medical needs. Of course, always consult your doctor if you have any adverse effects from using CBD oil, and stop using it immediately.

Q: How do you use CBD oil?

CBD oil can be used in so many different ways. We believe it’s important first to decide what you want the CBD to accomplish. If you’re going to treat asthma, you will want to use CBD in a different way than if you’re going to use it to treat joint pain. This is because the way your body absorbs CBD oil is important. If you want to treat a specific area of your body – say pain from a skin rash – you will want to use it directly on the area you want to treat.

Here are the most common ways to use CBD oil:

Sublingually (under the tongue)

Dripping it underneath your tongue is the most common way to use CBD oil. This is the most versatile and easiest way to use CBD. There’s no trick to it, you simply drip, and you’re done! This method is best for a long-lasting CBD effect. Using it in this way is great for treating epilepsy, sleeping disorders, depression, and chronic pain.

Inhalation (using a vapor)

You can use a “vape pen” to inhale CBD oil by mixing CBD into your vape mixture. This is the fastest way to get CBD into your bloodstream. However, it doesn’t produce a very long-lasting effect. This is great for treating asthma, sleeping disorders, and depression. It is also great for very quick pain relief.

Digestion (using edibles and capsules)

You can use edibles and capsules to get CBD into your system. This is one of the tastiest and easiest ways to use CBD oils. However, the CBD effects can take quite a while to kick in – especially if you have a full stomach. This method is great for nausea, reducing pain – and it can even act as an anti-inflammatory.

Topical use (rubbing into the skin)

You can rub CBD oil right into your skin to directly treat problem areas. This takes much longer than most methods, but it can bring pain relief to specific areas of the body for a longer period of time. This method is great for treating arthritis, skin problems, and pain areas. There are many CBD beauty products now available on the market. You can even find CBD topicals, facial creams, body lotions, and lip balms. This can be great for treating conditions that cause dry, tender, and inflamed skin.

The Best CBD Oil Brands for Anxiety & Depression

In the past several years, CBD has become a popular and natural way for people to help manage their anxiety. What is the best CBD for anxiety? And how does CBD help with anxiety? In this article, we highlight our favorite brands of CBD for anxiety and provide important background information on how to use CBD oils to help manage anxiety and depression.

CBD stands for cannabidiol, and it is one of the active ingredients found in cannabis. Though CBD is a critical component in medical marijuana, most commercially available CBD products are derived from the hemp plant. These products are said to offer a range of personal health benefits, and one of the most significant of those benefits is relief from anxiety.

A Harvard report notes that CBD is commonly used as a way to manage anxiety symptoms, and that those who struggle with various mental health concerns may use CBD to help them combat sleeplessness.

But what does the science really say about using CBD oil for anxiety and depression? And for those who wish to use CBD products to help with anxiety, what are the best CBD for anxiety brands out there?

Does CBD Help for Anxiety?

Studies show that, while CBD doesn’t necessarily alter a person’s baseline anxiety level, it may be useful for reducing experiential anxiety. Indeed, research points to CBD as a potentially effective way to address the symptoms of seasonal affective disorder (SAD), generalized anxiety disorder (GAD), and post traumatic stress disorder (PTSD). Additional research indicates that CBD “has a promising role as alternative therapy in the management of anxiety disorders,” though more clinical testing is needed to verify safe dosage levels.

Based on the available evidence, CBD may potentially help manage the symptoms of anxiety, though it is not a cure. Be sure to consult with your primary care physician or mental health care provider before taking CBD for anxiety and depression if you have any questions or concerns.

Best CBD Oil for Anxiety in 2022

Each product featured here has been independently selected by the writer. You can learn more about our review methodology here. If you make a purchase using the links included, we may earn commission.

  • Best Overall – CBDistillery Strongest Full Spectrum – Spruce
  • Best Full Spectrum – NuLeaf Naturals
  • Best Organic – Cornbread Hemp

How We Chose CBD Product for Calming

When creating our list of the best CBD oils for anxiety and depression, we compared brands and products ib six specific categories.

  • Type of CBD — Does the brand use full spectrum, broad spectrum, or CBD isolate?
  • Strength — How many milligrams of CBD does the oil contain per recommended dose?
  • Source — Where does the get the hemp used in their hemp extract? Is it grown in the U.S.?
  • Flavor — Do they offer multiple flavors, and if so, do they use natural flavoring instead of artificial flavors?
  • Transparency — Is the product tested by an independent third-party lab and do they make the results easy to access?
  • Customer Experience — What are customers saying about the product and if it has helped them manage stress and anxiety?
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Learn more about each of the CBD oils on our list below.

Our Complete Reviews & Opinions

Best Overall: CBDistillery

CBDistillery is known for high-quality, pure CBD products, and their full spectrum oil is a great choice to help you relax. All of their products are third-party lab tested and confirmed to be safe and effective. We like their Relief + Relax CBD oil because it is a full spectrum oil that provides plenty of additional active cannabinoids and plant compounds like CBG, CBC, and terpenes to give you the full benefits of the entourage effect.

  • CBD: Full Spectrum
  • Strength: 33 mg CBD per serving (1000 mg per bottle)
  • Hemp source: Colorado

Why buy: We love this strong full spectrum CBD oil for anxiety because it is sourced from non-GMO, U.S. Hemp Authority Certified hemp grown in Colorado. Taking CBD Relief + Relax in the morning may be a great way to support a sense of calm throughout the day.

Strongest Full Spectrum: Spruce

Spruce CBD oil checks all of the right boxes: it’s all-natural, made from USA-grown hemp, and is backed by rigorous third-party lab testing. You can get this lab-grade CBD oil tincture in a range of potencies, ranging from 750 mg to 2,400 mg per bottle. We like that Spruce CBD oil is all-natural, organic, vegan, gluten-free, and contains no artificial flavors, preservatives, or sweeteners. Note that Spruce products may be too strong for entry-level customers.

  • CBD: Full Spectrum
  • Strength: 25 mg to 80 mg of CBD per serving
  • Hemp source: Kentucky and North Carolina

Why buy: We love that Spruce offers some of the strongest full spectrum CBD products, including their extra strength formula with 80 mg of CBD per serving. We recommend it for experienced CBD users looking for powerful relief from feelings of anxiety and stress.

Best Full Spectrum: NuLeaf Naturals

NuLeaf Naturals CBD oil is about as natural as a CBD tincture can get. It’s made from organic hemp, it’s additive- and pesticide-free, and it’s carefully lab-tested by independent third-party labs. This Colorado-grown, full spectrum CBD offers the full benefits of hemp extract in a natural, organic product. It may be taken daily to help you manage stress and feelings of anxiety by promoting a sense of calm and wellness.

  • CBD: Full Spectrum
  • Strength: 30 mg of CBD per serving (1800 mg per bottle)
  • Hemp source: Colorado

Why buy: We love this strong full spectrum CBD oil because of its simplicity. It contains organic full spectrum hemp extract and organic virgin hemp seed oil. NuLeaf Naturals also provides a consistent concentration of CBD across all bottle sizes to make dosing easier.

Best Organic: Cornbread Hemp

To make their Distilled CBD Oil, Cornbread Hemp extracts CBD only from hemp flowers. This distillation allows the oil to maintain a full spectrum of cannabinoids, with a CBD-to-THC ratio of 27:1. Lower in THC than their Whole Flower oil, this product is better for finding comfort during the day while staying focused and alert. Cornbread Hemp CBD is USDA organic and offers a cleaner tasting oil than some whole plant extracts.

  • CBD: Full Spectrum
  • Strength: 50mg per 1mL serving
  • Hemp source: Kentucky

Why buy: We love this Cornbread Hemp Distilled CBD Oil because it uses whole flower CBD extract for a cleaner product and milder taste. It may be a great way to help ease anxiety during the day without drowsiness or loss of focus. Plus, it’s USDA-certified organic with third-party, ISO certified lab tests on every batch.

Using CBD to Help With Anxiety & Depression: What the Research Says

As cited above, initial research has found that CBD has the potential to help manage the symptoms of anxiety in a variety of cases.

There is also clinical evidence to suggest that CBD can be a tool for managing panic attacks. Panic disorder (PD) impacts about five percent of the total global population, making the anxiolytic effects of CBD products potentially impactful on a widespread level.

There is even clinical evidence that CBD may help minimize the symptoms of obsessive compulsive disorder (OCD), a nervous condition that can be debilitating. Currently, OCD is treated primarily through cognitive behavioral therapy and antidepressants, but the recovery rate is exceedingly low. The prospect of CBD as an alternative intervention is potentially game-changing.

But how exactly does CBD impact those with anxiety conditions? The short answer is that products from the cannabis plant tend to have a strong, reactive effect with the endocannabinoid system, a molecular system that regulates many core functions of the body, including emotions. Cannabinoids can bind to receptors in the endocannabinoid system and modify the way they function, yielding a range of possible health benefits.

In fact, one study notes that “modulating the activity of the endocannabinoid system turned out to hold therapeutic promise in a wide range of disparate diseases and pathological conditions, ranging from mood and anxiety disorders, movement disorders such as Parkinson’s and Huntington’s disease, neuropathic pain, multiple sclerosis and spinal cord injury, to cancer, atherosclerosis, myocardial infarction, stroke, hypertension, glaucoma, obesity/metabolic syndrome, and osteoporosis, to name just a few.”

While CBD may potentially help to manage stress and anxiety, it is not intended as a cure for anxiety or depression.

How to Choose CBD Oil for You

When you’re looking for the best CBD for depression and anxiety, it’s important to choose a product that is safe, effective, and natural. Here are some important things to keep in mind when shopping for CBD.

What to Look For

Always look for the following pieces of information when comparing CBD oils for anxiety: type of CBD, hemp source, strength, and lab testing. Below are more details on what each of these mean and why they matter.

Type of CBD

There are actually three different types of CBD extract, including full spectrum, broad spectrum, and CBD isolate. We typically recommend full spectrum products as the most effective, as they allow you to benefit from the full entourage effect of the hemp extract. However, if you undergo drug testing for work or are sensitive to THC, broad spectrum products offer many of the same benefits without the THC. This can also be important for those who find that THC negatively impacts their anxiety.

Hemp Source

The quality of the CBD is directly related to the source of the hemp used in a product. Always look for brands that use hemp grown in the U.S.A. We also recommend brands that use either USDA organic hemp or hemp grown using organic farming practices. This ensures that the plants do not contain any pesticides and or artificial fertilizers.

Strength

It’s important to know the concentration of CBD in a product so that you can take the appropriate dosage level. For those new to CBD, it’s generally recommended to start with a lower dose, 10 mg or less, and slowly increase the amount as you are comfortable to find the right level of relief. Extra strength products, with 30 mg or more per serving, are recommended for those who know how CBD will affect them. You can read more about the strongest CBD oils here.

Lab Testing

Only purchase CBD oils for anxiety that undergo independent third-party lab testing for quality and safety. This is critical to ensure that the product contains the correct levels of CBD and cannabinoids, and that it is free from toxins, heavy metals, or other harmful substances. The brands we recommend all make their lab test results available through QR codes on the product label or on their site.

How to Read Labels

When you check the label of any CBD product, look for information on the four key factors listed above. Labels should clearly state the type of CBD and if it was made with U.S. grown hemp. To evaluate the strength of the product, look for both the amount of CBD per bottle, usually in milligrams per 30 mL, as well as the amount of CBD per serving, usually in milligrams per 1 mL dropper.

Quality products should also include lab-testing certification and a way for you to verify the results for yourself. You can also look for industry certifications and seals from the USDA, Leaping Bunny, the GMO Project, and the U.S. Hemp Authority. Finally, take time to check the list of ingredients to make sure that you are not allergic to any of them. Most CBD oils use a carrier oil like hemp seed oil, olive oil, or MCT coconut oil.

How to Use

For most CBD oils, take a dose once or twice per day, depending on the amount. Some oils work better for daytime use and can be taken in the morning, while others are better suited for nighttime use to help you fall asleep. Again, if you are new to CBD, start with a low amount and slowly increase it to find the correct level to provide relief.

The amount of CBD needed may vary from person to person based on their level of anxiety and other health concerns. One thing that holds true across the board is that using CBD consistently is best for improving stress levels, as the compound builds up within the body, amplifying its effect. In other words, CBD may help you manage anxiety symptoms, but don’t expect it to take effect immediately.

Safety & Side Effects

According to the Mayo Clinic, CBD is generally well-tolerated. There are, however, some mild side effects that can occur. These often result from taking too much CBD, and can include:

  • Dry mouth
  • Diarrhea
  • Reduced appetite
  • Drowsiness
  • Fatigue

Additionally, CBD can potentially interact with certain prescription medications, like blood thinners and certain forms of statins. Always check with your doctor if you plan to start using CBD alongside any prescription medications. No CBD product has been approved by the FDA to treat anxiety or depression, so be sure to do your own research on any product you choose to purchase.

Alternative Options

While CBD may be a great option to help supplement your anxiety management, it is not meant to cure or treat anxiety. If you are suffering from severe anxiety and depression, the best thing to do is speak with your primary care physician or a mental health professional. They may recommend things like cognitive behavioral therapy, journaling, exercise, yoga, or prescription medications to help.

If approved by your doctor, CBD for depression and anxiety may work with these other approaches to help you find relief and better manage stress.

Josh Hurst is a journalist, critic, copywriter, and essayist. He lives in Knoxville, TN, with his wife and three sons. As a writer and independent reviewer of CBD products, Josh covers the relationship between cannabis-based products and the human body. His writing has appeared in Health, Shape, and Remedy Review.

Medically Reviewed By:

Alan Carter
PharmD Scientific Advisor, Medical Reviewer, and Clinical Pharmacist
Adjunct Faculty, UMKC School of Pharmacy