CBD for Dogs And Its Interaction With Other Medication
Dog CBD interaction is a reaction between CBD and the other drug your dog is taking. These days, more and more people are now including CBD in their dog’s everyday life.
However, is CBD oil interacting with other medications okay? Below, we’ll tackle if dog CBD can have a negative side effect on dogs taking other medication.
The benefits of CBD are great and are a safe supplement in general. However, will it complement other medications? Well, it depends on the drug they are taking.
Dog CBD Interaction with Medications
CBD and Rimadyl interaction for dogs
Rimadyl is a Non-Steroidal Anti-Inflammatory Drug or NSAID. NSAIDs are a class of drugs prescribed to manage pain or reduce inflammation in dogs.
Studies have shown that it doesn’t have any drug interaction with CBD. But that doesn’t mean it will not exist in the future.
In this case, dog CBD interaction will depend on the dog’s body chemistry and the dosage of CBD or Rimadyl. CBD can help maintain the dog’s well-being and balance with proper dosage.
CBD and Melatonin Interaction for Dogs
What even is Melatonin? Melatonin is a hormone released by the pineal gland in the brain that helps regulate the dog’s sleep and even waking up.
The powerful combination of CBD and Melatonin helps the dog’s wellness support. Some of the benefits found in CBD and Melatonin provide the same effects for your dogs.
CBD is known for its calming properties. Melatonin, on the other hand, provides comfort and restful sleep. This combo can work together to help maintain the dog’s well-being and proper rest.
CBD and Benadryl for Dogs
Benadryl is an antihistamine that is given to dogs that experience allergy symptoms.
It is usually prescribed by vets to treat environmental allergies or allergies caused by insect bites or stings.
It works by blocking the histamine (H-1) activity that causes allergic symptoms on a dog’s body. There is no known interaction between Benadryl and CBD.
But there can still be risks. CBD and Benadryl are both metabolized through the cytochrome P450 Enzyme System. This can increase the chances of doubling the side effects of both CBD and Benadryl.
It can potentially cause severe drowsiness or fatigue. We suggest checking with your vet before combining these two.
CBD And Glucosamine Interactions
CBD and Glucosamine can be an excellent combination for a dog that suffers from joint problems like arthritis or joint pain in general.
Glucosamine is one of the most popular over-the-counter arthritis medicines. It is usually given to manage pain on the joints caused by hip dysplasia. Glucosamine can also help with the treatment of spinal disc injury.
With the two-punch combo of CBD and Glucosamine, it can help reduce pain and inflammation from your dog’s joints.
CBD and Prednisone for Dogs
Dog CBD interaction with Prednisone is not recommended for dogs. Prednisone is a prescription steroid used to reduce inflammations, treat allergy symptoms, arthritis, and more.
CBD and Prednisone together are not recommended for dogs as they can increase the side effects of both. They are both inhibitors of the CYP450 Enzyme System.
If you’re planning to give CBD oil to your dogs while they are on different medications, it is best to consult with your vet in these situations.
CBD and Meloxicam Lethal Combo for Dogs
Meloxicam, likewise Rimadyl, is a Non-Steroidal Anti-Inflammatory Drug or NSAID. Meloxicam is prescribed as a pain killer that helps ease inflammation in dogs.
There is a chance that taking NSAIDs with CBD can increase the effects of these pain killers. It all comes down to proper dosage on meds and supplements.
You, as the owner, have the responsibility to research, talk to your vet, and monitor your dogs when taking the CBD route in addition to meloxicam.
Commonly Asked Questions
Will Benadryl help with Dog Anxiety?
Well, yes and no. You have to identify what kind or cause of their anxiety.
Benadryl can help reduce dog anxiety symptoms. It is also used as a sedative to help dogs during fireworks, thunderstorms, or traveling. But overall, Benadryl is not helpful for dogs struggling with anxiety or phobias.
It has high efficiency in helping dogs with motion sickness. However, it can have opposite side effects on rare occasions where your dogs will be hyperactive rather than sedated.
Proper Dosage of Benadryl for Dogs
Giving dogs about 2-4mg of Benadryl for every kilogram of body weight is good. However, it is still best to consult with your vet and wait for their approval before you take action.
Administering the correct dosage of Benadryl for dog anxiety is crucial. The wrong amount can have serious consequences.
How often do I give CBD oil to my dog?
This all depends on the dog’s condition. Some dogs can benefit from daily doses, and others can not.
For example, dogs suffering from arthritis or seizures can benefit from a daily or twice a day dose of CBD between 2-8mg/kg or lower. An interval of eight to twelve hours is advised when CBD twice a day.
A good rule of thumb when administering CBD oil for your dog is 1-5mg CBD for every 10 pounds of their body weight.
What happens if your dog takes too much CBD?
CBD is a non-toxic and non-psychoactive compound meaning it will not get ‘high’. However, when taken too much intense, concentrated CBD, potential side effects can develop.
A few of these symptoms are lethargy (lack of energy), vomiting, drowsiness, urinary incontinence, and hypersensitivity.
Dog CBD Interaction with other Medication Summary
Due to a lack of research, there are still many things that we don’t yet know about the world of CBD, not just for humans but also for dogs. But we cannot deny the great benefits of CBD for dogs.
When giving CBD to our dogs, there are still many things to consider. We must focus not only on the correct dosage but also on other medications that they need.
Studies showed that CBD has no known interaction with medications, but it doesn’t mean it will stay like that. Dog CBD interaction will depend on the dog, CBD, and the medicine.
Our vets usually prescribe these medicines. It is still the best choice to consult with your vet in CBD drug interactions.
Since the FDA doesn’t regulate CBD products yet, most US Veterinary and Pharmacy boards are advised to avoid prescribing or discussing CBD until further notice.
Always remember that you are the one in control when it comes to CBD oil drug interactions.
You have the power to help your dogs maintain a well-balanced life. Research, consult with your vet, and monitor.
Cbd oil for dogs on prednisone
By Andrew Gora
June 03, 2020
No matter who you are, your dog quickly becomes a treasured member of the family, and like any family member, they will get sick at some point. And, just like any other member of the family, you will go above and beyond to help them get better. One treatment for this is prednisone, a standard solution used by veterinarians everywhere. However, is it all it’s cracked up to be, or is there a better way?
What is Prednisone?
Prednisone is a steroid used to treat inflammation in your dog while also assisting its immune system. It is stronger than the naturally released cortisol, and it is converted to prednisolone in your dog’s liver . If your dog has a weak liver function , vets may skip prednisone altogether, and instead prescribe prednisolone to save on conversion.
As it can treat a wide range of diseases and conditions, prednisone is a popular option for ensuring your dog gets back to its silly and energetic self. However, as with many treatments out there, it does come with side effects that you may want to avoid.
Why is Prednisone Bad for Dogs?
These side effects can range from increased thirst to lethargy, and while these may not be considered too extreme, they can still have adverse effects on your dog’s health . This is especially true when side effects compounds. For example, increased thirst can lead to more frequent urination, but as another side effect of prednisone is infrequent urination in dogs, it could cause an infection .
Other side effects include increased appetite , which can cause discomfort, and it can also take longer for wounds to hea l, which is especially concerning if your dog gets sick or injured easily during his or her routine walk.
Furthermore, vomiting and diarrhea are other possible side effects, and this can happen even if your dog does not overeat during mealtime.
There is also a chance that it could affect their overall behavior, becoming more aggressive. After all, no one wants their dog to snap, bark, or growl at guests, strangers, or even their family members, and if you have other pets and small children, this could be a cause for concern.
There are also long-term risks associated with prednisone prescriptions and treatment, primarily if you use the steroid for an extended time. Conditions such as Addison’s disease, Cushing’s disease, diabetes, heart problems, or even heart attacks are potentially fatal issues, so it’s worth understanding alternatives to using prednisone to treat your dog’s health problems.
Looking for delicious treats that will also alleviate your dog’s pain and anxiety? Dope Dog has everything you need to make your dog happy
Why Should You Use CBD Instead?
Using CBD for treatment is a superb and all-natural alternative to pharmaceutical medications. These solutions, which you can find on the Dop Dog store, can get your dog back to perfect health just as quickly, and without the same issues that you might encounter with prednisone.
As an all-natural ingredient, you can trust that CBD treatment is entirely non-toxic . This helps reduce the risk of side-effects and will focus only on treating whatever issues your dog may suffer from.
It’s more affordable.
If you thought medicine was expensive for humans, medicine for dogs, or any pet, is on a whole other level. As a dog owner, you know you will do anything it takes to ensure your dog gets back to its usual self, so you are willing to spend whatever you need to make sure that happens.
CBD treatments are more affordable than other medical treatments , which is excellent news for anyone on a budget or looking for a natural and affordable solution. Plus, with the extra money you save on medicine, you can start planning your next doggy-and-you vacation. We hear the Rockies is terrific this time of year.
It treats many common problems.
From cancer pain to anxiety, CBD can treat a range of issues your dog might encounter. As it is all-natural, there is no need to worry about extreme side effects. It can also fight off potential cancer cells, reduce aggressive behavior, ease anxiety , and help with arthritis. This ensures that your dog will bound around the park for many, many years to come.
Your dog won’t get high off it.
There is zero THC , the psychoactive component of cannabis; you don’t need to worry about your dog getting high and eating all of the snacks in the cupboard.
While CBD can be useful for treating your dog for a range of problems, illnesses, and diseases, it is not entirely perfect . As with anything you allow your dog to ingest, you must understand the cons as well as the pros.
It can still make them lethargic.
As your dog will not be used to CBD as medication, there is a chance that it may become less energetic when you start using it . Because of this, it’s worth starting the treatment in small doses to get them used to the effects.
You can still encounter problems if you give them too much.
Likewise, giving your dog too much CBD treatment can have effects on your pooch. You must follow the application guidelines to prevent this from happening.
Even with these cons, there are still more pros for using CBD as a treatment for your dog . With this in mind, it’s worth considering your options the next time your dog appears to be suffering from anxiety or more significant problems to see whether CBD is the solution.
Looking for quality CBD products? Dope Dog has a wide selection to keep your canine companion smiling for life.
If your dog is sick or ill and you want an all-natural remedy to get them back on their feet, so you can start going on adventures again, then take the time to consider a CBD rather than prednisone. For all your doggy’s CBD needs, don’t forget to check out the Dope Dog store , as well as embrace the wealth of detailed information on this blog!
Steroids vs. CBD: A Topic of Truths and Transitions
Chances are that most humans and pets have been prescribed a steroid medication at some point in their life for treatment of one or more medical conditions. Whether it be for inflammation, allergies, or another type of illness, injectable and oral steroids have been applied by doctors and veterinarians for decades as a part of treatment plans due to their effectiveness in addressing numerous symptoms quickly and effectively. However, although the relatively fast effects felt by starting a steroid may be impressive, long-term use can and very often lead to serious side effects, both in humans and pets. Moreover, despite newer age doctors trying to move away from heavy use and dependence on steroids, this class of medications is still to this day used more than it should be, given that we know now what they likely lead to over time.
In comparison, CBD and other cannabis-based therapies have recently been found to effectively address a majority of the same symptoms steroids remediate, but do not tend to cause any of the same adverse long-term side effects steroids come with. Therefore, there is a huge potential promise in considering CBD as a legitimate therapeutic substitution for steroids when developing a safe and effective therapeutic treatment plan. Ultimately, when a life of longevity, health, and happiness is the long-term goal, understanding the ramifications and alternatives to steroid therapy is critical for the well-being of patients, including your pet.
Table of Contents
What are Steriods?
The term “steroid” simply describes a class of molecules that have a variety of influences and effects within an animal’s body. Specifically, there are “natural steroids” which our bodies make on their own, and “synthetic steroids” that are produced in laboratories that overlap with our internal bodily systems.
Steroids became widely popular in the 1940’s for inflammatory conditions . Corticosteroids in particular were and continue to be used to treat symptoms associated with arthritis and other degenerative musculoskeletal conditions. In fact, in 1950, the Nobel Prize for Physiology or Medicine went to Dr. Philip Hench, Edward Calvin Kendall, and Tadeus Reichstein for the discovery of cortisone and its applicable uses with rheumatoid arthritis.
Since their discovery and explosion onto the medical scene, steroids eventually became widely over-prescribed, as they were viewed as the “miracle drug” that could help with any and all conditions in conjunction with those initially known. However, as the repercussions of long-term use then began to surface as well, a shift towards healthier, long-term substitutions has slowly begun. Many doctors and veterinarians now only prescribe steroids for short-term applications and rely on multimodal therapies to promote long-term control of the underlying illness(es). However, many other medical professionals have not yet adopted this pattern, and still use steroids more often than is thought to be safe or required. T here are a small number of situations where steroids must be used for long-term immunosuppression (including some refractory autoimmune diseases and Addison’s Disease), but again, these are rather uncommon. Unless your pet has one of these conditions, steroids should be considered a short-term solution only.
The most common steroids prescribed by most veterinarians are prednisone, prednisolone, hydrocortisone topicals, and TEMARIL-P . Steroids do, in fact, reduce inflammation in the body, but not without a cost. The most common side effects of early steroid use include polyuria (excessive urination), polydipsia (excessive thirst), polyphagia (excessive signs of hunger despite not actually requiring more food), and panting. Steroids are also well-known for their serious, and sometimes dangerous, side effects including:
- Weight gain
- Salt and fluid retention
- Cardiac Problems (Heart)
- Increased secondary infection risk
- Slower wound healing
- Loss of muscle mass
- Hepatic Problems (Liver)
“ If any of the following serious side effects occur, stop giving Temaril-P and seek emergency veterinary medical attention ; an allergic reaction ( difficulty breathing; swelling of the lips, tongue or face; hives ). Trimeprazine can cause drowsiness, tremors and muscle weakness . Prednisolone may cause symptoms of Cushing’s disease which include increased thirst, urination and hunger as well as vomiting and diarrhea . Other side effects may also occur. Talk to your veterinarian about any side effect that seems unusual or bothersome to your pet. Do not give any other over the counter or prescription medications, including herbal products, during treatment with Temaril-P without first talking to the veterinarian. Many other medications can interact with Temaril-P resulting in side effects or altered effectiveness. These include sedatives, anesthetics, pain medications, epinephrine and procaine.”
As stated above, there are few cases where lifetime use of steroids is necessary. But, in the majority of cases where it is not a necessity, the body will become susceptible to developing one or more of the many side effects listed, and will also be subject to dependency and severe withdrawal effects if steroid therapies are discontinued too quickly. That’s why doctors generally advise a gradual tapering protocol off of steroids toward the end of a long-term treatment plan. Ultimately, if a steroid has been used for more than 7 days, then it is not advisable to stop this medication abruptly without the supervision of a medical professional, as this can prove detrimental to your pet’s health as well.
What are Steriods Used for?
Oral steroids are the most commonly prescribed medication for dogs (and us). These medications again are synthetic steroids, meaning they are not naturally produced by our body . They are most often prescribed to treat inflammatory conditions, skin conditions, non-infectious respiratory diseases, and degenerative neuromusculoskeletal conditions.
According to Dr. Gary Richter , “ steroids are some of the most powerful anti-inflammatory medications available .” Because of this, they tend to be a commonplace treatment for pets with skin and respiratory conditions. Dr. Richter continued to state, “ despite steroids’ ability to reduce inflammation, their long term side effects far outweigh their benefits .”
CBD is being researched as a ‘steroid-sparing option.’ A study published in Current Neuropharmacology indicated CBD has therapeutic benefits for both people and pets who suffer from chronic pain. There is an abundance of compounds found to reduce inflammation in both us and our pets. The most common phytocannabinoids found in the Cannabis plant, THC and CBD, both possess anti-inflammatory properties. Other minor cannabinoids, including CBG, CBC, and THCV were also found to provide anti-inflammatory properties as well.
According to Future Medicinal Chemistry , “ cannabinoids have exhibited significant potential to be used as novel anti-inflammatory agents and specific targeting of CB2 receptors holds the promise of mediating immunosuppressive effects without exerting psychotropic side effects.”
A Baylor College of Medicine study, using In vitro and in mouse models, found that CBD significantly attenuated the production of proinflammatory cytokines IL-6 and TNF-α while elevating levels of anti-inflammatory IL-10. In the veterinary study, CBD significantly decreased pain and increased mobility in a dose-dependent fashion among animals with an affirmative diagnosis of OA.
According to a veterinarian named Steven Katz , who is one of only a few doctors applying CBD-based therapies in practice, “our experience in my clinic has shown cannabidiol (CBD) is an effective treatment in reducing inflammatory response . We have a passion for improving dogs’ quality of life, and we look forward to learning all we can about therapeutic methods to achieve this.”
The Ultimate Question: Steriods vs. CBD
First things first: If you are reading this and your dog is already taking steroids, it’s absolutely critical the regimen is not stopped immediately. Never attempt to taper this medication without the supervision of a licensed veterinarian.
Taking a full-spectrum CBD-based product in combination with a steroid, like prednisone, will most likely (not guaranteed) not result in any detrimental adverse effects. Although both compounds are broken down by the liver, taking both at the same time is unlikely to cause “liver overload” unless the liver is already unhealthy (which would have been or can only be determined by submitting bloodwork with your veterinarian). If the liver is already “sick” then there may be hypothetical concerns regarding administering both at the same time, even though research up to this point has not proven such statements. The reason for this is because research indicates that CBD and other cannabis-based molecules are broken down by the “cytochrome p450 enzyme” group located in the liver, and that CBD specifically inhibits a component of the activity of a particular enzyme (CYP3A4) which is used by the body to break down numerous other molecules. The effects of this are still not entirely known, but with an unhealthy liver, it is highly advised to be more careful when considering any extra stress it may cause on this organ. We do know that Prednisone does cause liver “induction” resulting in numerous secondary effects, both on the liver’s functioning ability and its ability to handle other molecules simultaneously, such as CBD and the other active compounds in a full-spectrum product. Again though, each animal is an individual, and therefore, each case must be addressed individually before making any decisions or conclusions.
Of course, given what we know about steroids and CBD, we should all desire to get more pets off of long-term steroid use, and if appropriate, use a properly-vetted Full Spectrum Hemp CBD-based therapy to address the conditions steroids were originally applied for. But, this transition must be done responsibly. The overall goal is and should always be to promote a lifestyle of optimum healthiness and happiness. With the proper diet, natural supplements, and safe remedies in times of illness like a properly vetted full-spectrum CBD-based product, there is an opportunity to enhance and maintain your pet’s overall well-being without abusing and over-using pharmaceuticals, in an age where pharmaceuticals still seem to be king.
Dr. Zac Pilossoph
Dr. Zac Pilossoph, a Long Island, NY born, nationally recognized veterinary medical professional, a top graduate of Tufts University Veterinary School of Medicine with post-graduate focused training in E/CC and Neurology/Neurosurgery at two of the most recognized programs in the country, and a young multidimensional serial entrepreneur, has rapidly and collaboratively helped promote a new wave of global evolution and individual empowerment in more ways than one. In addition to developing and launching several novel platforms in the veterinary and mental health fields, he is now quickly joining some of the most reputable leaders in the cannabis education and innovation space. Dr. Pilossoph is determined to synergize with colleagues, allowing evidence-based information to fuel a rapidly expanding industry. As one of the world’s most proactive cannabis-focused experts in his respective industry, Dr. Pilossoph provides tremendous value by delivering non-bias, harm reduction education, via both large-scale speaking engagements and individualized consultations, to the global cannabis pet and vet industry. Further, he is a Certified CBD Professional Educator through the CBD Training Academy and has started a nationally influential multi-tiered cannabis brokerage firm titled Excelsior Honour Associates. Lastly, he acts as a consultant for the CBD product space in order to impart as much quality, control, and consistency across the industry as much as possible. Ultimately, through candid education, fierce collaboration, and constructive evolution, Dr. Pilossoph is reversing stigmas and advancing the safe and effective consideration of cannabis into society, for all creatures on Earth.