Healthy tokyo cbd oil for seizures

How much CBD oil should I take?

“I bought CBD oil, but I don’t know how much to take…” This is a comment we hear often. Many people also wonder what happens if you take too much CBD? Here, we will thoroughly introduce the reasons why CBD daily intake numbers are not clearly set, precautions for taking CBD, and advice on intake by application and product.

The amount of CBD required is different for each person

People who drink alcohol can become energetic and excited at first, but after drinking a bit more may become calm. In the case of a small amount of alcohol, it can act as a stimulant, but when a certain amount is consumed, it can have a suppressive effect. While the mechanism of alcohol and CBD are very different in your body, use of CBD can provide focus or relaxation as your body may react differently to smaller versus larger amounts taken. Research shows that a small amount of CBD suppresses alertness, improves concentration, relieves anxiety, and raises mood, while a large amount of CBD can have the effect of causing drowsiness, relaxation, or a sense of wellbeing.

Tolerance for CBD can vary from person to person as far as the amount required to reach a state of relaxation. This comes from the fact that every individual has their own biological system.

In addition, the endocannabinoid system in our bodies are different from person to person, so the amount of CBD required can also vary. According to Dr. Dustin Slack, a doctor of osteopathic surgery, some patients feel a therapeutic effect with just a small amount, while others prefer to take larger amounts. However, this does not mean it is best to take large amounts of CBD. Taking low doses over a long period of time may help alleviate chronic symptoms and prevent disease recurrence according to overseas data.

Therefore, it is important to know the appropriate amount of CBD that is right for yourself. Referring to the following guidelines for daily intake, first start of with a lower amount and then if necessary increase gradually while gauging the reaction of your body. Please keep in mind that the “right amount” can also depend on changes in your physical condition and lifestyle, so please always adjust while keeping in tune with your body. CBD is said to have many different uses, and the estimated intake varies depending on your reason for taking CBD.

Advice on CBD intake by application

For relaxation, anxiety and inflammation

If you are using CBD for the first time, please start by taking 15 mg of CBD twice a day. Other sites may recommend more or less, but HealthyTOKYO, based on feedback from many customers over the years, recommends to start with 15 mg and adjust as necessary. Please try the same amount for a few days and adjust the amount little by little while checking the compatibility with your body.

For a better sleep

If you want to take CBD to encourage sleep and better quality rest, try taking about 15-30mg before going to bed. It seems better to have a larger amount before bedtime, compared with what would take during the day.

Improvement of autism symptoms

In addition to reducing anxiety and promoting calmness, CBD is said to be effective for autism according to information from Europe and the United States. While not a treatment for autism, it can be used to relieve symptoms. In this case, try taking 15mg of CBD to start.

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When used to treat epilepsy

It is known that CBD reduces the number of epileptic seizures and their severity. It is recommended that you consult your doctor about the appropriate dose. Here is some information that may provide guidance.

The FDA guidelines for EPIDIOLEX®︎ from the United States, the only CBD drug approved by the U.S. FDA (Food and Drug Administration), recommends that you start with CBD 2.5 mg/kg (patient’s weight) twice a day. After monitoring the outcome for a week, it is possible to raise the intake to 5 mg/kg, with a maximum intake up to 10 mg/kg.

EPIDIOLEX®︎ is a medicine applied to the treatment of seizures with Lenox Gasto Syndrome and Drave Syndrome, which are two type of epilepsy. This product contains other substances from cannabis, in addition to CBD, for a higher efficacy in the treatment of these conditions. The same effect may or may not be obtained with CBD oil alone. However, CBD is known for is effectiveness for epilepsy, and you can consider the above as a general guideline.

Recommended amounts for each CBD product

Let’s take a look at the recommended amount to take for each of the products available at HealthyTOKYO. Please keep in mind that the absorption is generally considered higher with oils compared to gummies and other edibles. With oils (tinctures), place the desired amount under your tongue (sublingual) and hold for 20 to 30 seconds before swallowing. With gummies, chew thoroughly to allow better absorption.

HealthyTOKYO Products & Recommended Starting Amounts

What happens if you take too much CBD?

There are individual differences, but basically it is said that CBD is safe to take up to about 1500 mg a day, and the WHO (World Health Organization) also acknowledges the safety of CBD.

Some studies have also suggested that if you overdose on CBD, it may cause liver disease. However, this is limited to people taking a excessive amount of CBD (far more than mentioned above) over an extended period of time. If you have any concerns, please consult your doctor before taking any CBD.

As another reference, the Food Standards Agency of the UK and the Food Standards Agency (British Food Standards Agency) announced in February 2020 that healthy adults should limit their daily CBD intake to 70 mg. That would be the equivalent of seven CBDTokyo Mango Star 9.3 Gummies or twenty-three drops of HealthyTOKYO Yuzu 6% CBD Oil.

Can CBD be used in conjunction with medication?

CBD can interact with some medication and cause and increase or decrease of their effect.

When taking most medicine, the body must break down and metabolize the substances in the liver. During this process, CYP3A4 is responsible for the metabolism of 60% of the drug. CBD can interfere with the function of CYP3A4 in some cases.

When medicine is prescribed, you may be informed by your doctor or pharmacist not eat grapefruit. CBD can work in a similar way to grapefruit by suppressing the enzyme CYP3A4 in the liver. In this case there is a risk that the efficiency of the drug may be affected by staying in the body for a longer time without metabolizing.

If you are currently taking medication and want to try CBD, we recommend that you consult your doctor to see if you need to be cautious by consuming them together.

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Let’s find the amount of CBD that suits you.

As mentioned above, the amount of CBD required varies from person to person, so it is important to find the amount and product that suits you. Depending on the application, it is usually appropriate to start with 15 mg at a time, and adjust while monitoring the results.

CBD for Epilepsy: Clinical Trials

CBD has been hailed for its variety of potential health benefits, from helping with issues such as sleeplessness, lack of concentration, and pains, to more serious conditions such as epilepsy. In this article we look into using CBD to treat epilepsy and the possible benefits. With clinical studies turning up positive results, using CBD for epilepsy has gained a lot of traction recently. In the United States, this is the first use of CBD approved by the FDA. In this second article of the HealthyTOKYO 10-part series on the potential benefits of CBD, let’s take a look at why using CBD for epilepsy should be seriously considered.

What is CBD

CBD, otherwise known as “Cannabidiol” is a chemical compound that comes from the Cannabis Sativa L. plant. This compound, called a cannabinoid, has been shown to interact with receptors in the brain and body, and is said to produce a number of beneficial results. CBD can be sourced from either marijuana or hemp, and in the latter case, it contains almost no THC.

For a more in-depth explanation about CBD, please also take a look at the other HealthyTOKYO articles on CBD, “CBD Oil and the Science Behind It – A Doctor’s Perspective” and “CBD for Depression”.

What is Epilepsy

Simply put, epilepsy is a condition that leads a person to have repeated seizures. 1 in 26 people in the US will be diagnosed to have epilepsy sometime during their life, and it is the fourth most common neurological disease. Seizures caused by epilepsy can vary in degrees of seriousness, from loss of body control (uncontrollable twitching) to mild blank staring. Even mild seizures can prove to be very dangerous in certain situations where constant control is paramount, such as driving or swimming.

CBD for Epilepsy

How does it work? Well, the exact science behind how CBD helps with epilepsy is still not entirely clear. As discussed in my previous article, “CBD for Depression”, CBD as a cannabinoid interacts with receptors in the brain, and it is through this function that we assume CBD can help alleviate epileptic symptoms.

The CBD medication Approved by the FDA

EPIDIOLEX, an oral solution containing 90% CBD was recently approved in the United States for treating two types epileptic syndromes, Dravet syndrome and Lennox-Gastaut syndrome. These two syndromes can develop in children from a very young age (around 2 years old and up), and have proven to be very difficult to treat with traditional methods, while potentially causing serious developmental damage.

CBD treatment by EPIDIOLEX is the first FDA approved medication to specifically help with Dravet syndrome, which affects between 1:16,000 and 1:21,000 people. In addition, research on the efficacy of EPIDIOLEX for epilepsy was conducted by means of the “Gold Standard”, wherein the researchers did not know which patients received CBD and which received placebo.

In a study with positive results conducted by Dr. Orrin Devinsky, director of NYU Langone’s Comprehensive Epilepsy Center in New York, doses of 10mg and 20mg CBD were administered to people who suffer from epilepsy. Nearly half the 225 patients with Lennox-Gastaut syndrome saw reduced levels of daily seizures when treated with CBD. There were 42% fewer seizures reported for those in the 20mg group and 37% fewer seizures for the 10 mg dosage group. It should be noted that the control group who were given a placebo also saw a reduction of 17% in seizures.

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Devinsky went so far as to claim that, “Compared to other drugs used to treat epilepsy, I think Epidiolex, which is 99-percent pure cannabidiol, has a better side-effect profile than many of the available drugs.” The negative side effects mentioned here seemed to be more prevalent to the group with a higher dosage (20mg) and included a loss of appetite, trouble sleeping, low energy, and change in liver function.

Anecdotal Accounts of CBD for Epilepsy

In addition to the aforementioned clinical trials, one can easily find a slew of positive testimonies from those who have tried CBD oils to treat their own epileptic symptoms or the symptoms of their loved ones.

Perhaps one of the most well-known stories of people using CBD to surprisingly positive results is the account of “Charlotte’s Web”, a young girl who suffered from hundreds of seizures every week from a very young age. Charlotte saw nearly all her symptoms disappear upon taking a high concentration CBD oil. Furthermore, there are a whole range of accounts from people on the internet who have shared their experience of using CBD for epilepsy. Below are a few comments from epilepsy.com’s forum members.

“We started (our daughter) on CBD after (she had) 11 seizures in one day…out of desperation, we used it. She has not had a seizure since!”

“I am an adult on CBD oil and it is controlling my seizures. I wish my parents had known about it and tried it. I take 1/2 dropper full per day. (For) a baby you could try a drop or two. No side effects so far.”

“I had been having anywhere from 6-10 seizures a week and this product, (CBD oil), has all but eliminated my seizures. I know that it will not cure epilepsy, but my point is that it has slowed the progression of seizures. I am down to an occasional 1 petit-mal* about every 2 weeks.”
*A petit-mal is a brief, sometimes unnoticeable, seizure, which is nevertheless dangerous as one of the symptoms can be a loss of consciousness.

CBD oil like those used by the forum members above can be acquired in Japan by means of an online seller. However, please make sure to confirm that the THC content is 0%, as THC is a strictly prohibited substance in Japan. Even certain hemp-based CBD oils can contain trace amounts of THC, so please confirm that the seller provides clear information and certification regarding their CBD products.

Conclusion

While it is very tempting to say that CBD is a viable treatment for epilepsy in general, keep in mind that the clinical trials sited in this article were specifically conducted in relation to Dravet syndrome and Lennox-Gastaut syndrome. Therefore, they do not necessarily provide evidence as treatment for all forms of epilepsy. If you would like to try CBD for epilepsy, do not do so without first consulting a doctor. If you would like to know more about CBD or anything else health related, please do not hesitate to use the HealthyTOKYO chat feature located at the bottom right of the screen.