How long for cbd oil to work in people

How Long Does CBD Oil Take to Work?

To understand how long CBD takes to work, you first need a basic understanding of what CBD is, and how different variables can impact its onset of action. In general, CBD is absorbed into the bloodstream within 20 minutes to 2 hours depending on the method of delivery. 1 Other variables like the dosage, full spectrum or THC-free, consistency, and quality can also play a role in how quickly you begin to feel the benefits of CBD. How long does CBD oil take to work? It really depends on your goals and expectations, along with other variables like your age, body weight, and metabolism.

However, for anyone trying CBD for a more serious issue, consistency and patience needs to be part of your wellness routine for the full potential of CBD to be realized.

  • 1) CBD Takes to Enter Your Bloodstream
  • a) Factor 1: Method of Intake
  • b) Factor 2: Dosage & Potency
  • c) Factor 3: CBD Quality
  • d) Factor 4: Individual Biology
  • e) Factor 5: Consistency
  • 2) Feeling Out How CBD Works for You
  • 3) What kind of CBD should I take?
  • 4) What time of day should I take CBD?
  • 5) How Often Should I Take CBD?
  • 6) How Long Does It Take for CBD to Work?
  • 7) After one month of CBD: how will I feel?

If you’d like to know more about what it takes to begin seeing results, read on as we explore the variables, but first watch my short video below!

How Long CBD Takes to Enter Your Bloodstream

As I mentioned above, the answer to how long CBD takes to work really depends on your own definition of the word “work.” Mild anxiety is going to be much quicker and easier to address than a more serious condition.

Simply put: the answer to this question isn’t a one-size-fits-all solution. It is a step by step approach that acknowledges how the benefits of CBD, and how long it takes to achieve them, may differ from different delivery methods and the issue at hand. For example: how long it takes CBD to work will differ drastically between sublingual oils, CBD capsules, and CBD topicals. So let’s get down to the nitty gritty!

Factor 1: Method of Intake

There are many different ways to consume CBD. Each of these methods has a different impact on how much, and how quickly, the CBD gets absorbed into your bloodstream. 2 This phenomenon is called bioavailability. It’s important to understand this because it will help you determine how much you’ll need to take to feel its effects; and you can also get an idea of how long it will take for your CBD to work.

CBD Bioavailability Chart

As you can see in the chart above, the consumption method of CBD is the biggest determining factor in how long it may take for CBD oil to work. The quickest and most bioavailable method of CBD consumption is through inhalation, but many states still prohibit the sale of CBD-rich hemp flowers for smoking. The next best is a sublingual oil or tincture, followed by ingestible CBD capsules and finally topicals.

Because CBD capsules have to travel through your digestive system, they have what’s known as a first-pass metabolism. This means that it’ll take longer to feel the effects of the CBD, or in medical terms – the bioavailability rate. (To clarify: this applies for all edible cannabis products, because all of them have to pass through your digestive system.)

On the other hand, CBD oil avoids first-pass metabolism by going straight through the capillaries under your tongue. This makes it the most effective method of delivery after smoking, and it means you’ll feel it quicker. 3 This is also the main reason we formulate our organic CBD oils with medium chain coconut oil. Because of its thin and viscous characteristics, it absorbs quickly when placed under the tongue.

There are other variables at play in how long it takes, but this should help you determine when your specific form of CBD will start working.

Factor 2: Dosage & Potency

The amount of CBD you’re taking every day will affect how quickly you will begin feeling its effects. In general, the more that you’re taking, the quicker you’ll feel it.

For example, if you take a high dose of CBD to Support a healthy Sleep Cycle, you’ll probably feel sleepy in about 15-30 minutes. In contrast, if you take a lower serving for general wellness or everyday aches or pains, it could take a few days of dosing to notice significant results. 4

How Much CBD Should I Take?

The bottom line is that when you’re choosing a CBD product, you should consider the type of results you’re trying to achieve and adjust your dosage accordingly. This may also include testing different consumption methods or a different application style. It can also depend on your body mass, and if you’re taking any prescription medications. 5

Everyone is different, and this is something you need to dial in for yourself. A full dropper of our 750 mg CBD oil is 25 mg, which we think is a great daily serving to start with. But some people take more, and some need less. CBD can be a powerful supplement, especially when it contains THC alongside it. So it’s best to consult with your doctor to determine the right dose for you and avoid any CBD side effects.

Factor 3: CBD Quality

We’ve said it time and time again: not all CBD products are created equally. Because this market is largely unregulated, many brands on the market do very little to maintain the quality of their products. 6 Some CBD brands use ingredients that have impurities, additives, and adulterants which will significantly effect the safety of your product. This is why you should always look for a third party lab test to know that you’re getting a high quality CBD product, along with the USDA organic seal.

We also recommend looking for a full spectrum CBD product, which contains more cannabinoids than just CBD. Just like CBD, these other cannabinoids don’t get you high; but they do have a synergetic effect that heightens your body’s response through the “entourage effect.” 7 One of those cannabinoids is probably one you’ve heard a lot about, and that’s THC. In order for a product to truly be considered full spectrum, make sure it contains trace amounts of THC. The legal amount is no more than 0.3 percent of total dry weight.

The origin of the raw hemp plant material is another key factor that determines the quality of your product. Hemp is a powerful bioaccumulator, meaning that it soaks up all the nutrients and toxins in the soil it grows in. If the soil isn’t pre-tested for toxins, pesticides, or heavy metals, those things could end up in your CBD. That’s why you should only use CBD products made from hemp grown in the USA, and preferably in Kentucky. In addition, if the farmer uses synthetic fertilizers, or if the field doesn’t go through a multi-year crop rotation, there will be fewer nutrients in the soil and the hemp will contain less CBD. 8

You can avoid all of these problems by opting for an organic cannabis product that’s been certified organic by the USDA. As we explore in this article, the USDA has strict guidelines for organic farming and processing. This means that USDA certified organic products will be responsibly sourced and of higher quality. 9

Factor 4: Individual Biology

Although you can count on certain effects to take place, no two people respond exactly the same to CBD, even if they have the same consumption, the same delivery method, and the same body composition. One person could feel their CBD tinctures in 10 minutes, yet someone else could take the same dose and feel it in an hour. 10

There are several key considerations that fall into this category, and they all affect the amount of time it will take to feel CBD’s effects.

Body Weight

Like most cannabinoids, CBD is fat-soluble. Those who weigh more tend to have more fat cells in their body, which means that they’ll absorb and store CBD for longer in their body.

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While this isn’t necessarily a bad thing, it does mean that people with more fat cells in their body will most likely need more time to adjust. It’s not all bad news, though: the higher your body mass, the longer it takes for CBD to work. 11

Metabolism

While individual metabolism does involve burning calories, it also affects how your body breaks down compounds like CBD. Depending on your age, your lifestyle, your digestive system, and your genetic profile, your metabolism can function at different rates. This is what we call our metabolic rate – and we all have different ones! 12

If you exercise regularly and have a high metabolism, you’ll feel the effects come on faster; but you’ll also feel it wear off more quickly. On the other hand, if you have a slow metabolism, you’ll notice that it takes longer to feel your CBD coming on; and it will stay in your body for longer.

Endocannabinoid Balance

CBD is part of a unique set of compounds called cannabinoids. These compounds interact with a biological system found in nearly all animals. It’s called the endocannabinoid system (ECS), and its cannabinoid receptors are found throughout your entire body. While we’re just beginning to understand how the ECS works, research suggests that it’s responsible for many of your biological functions like your mood, sleep, appetite, and pain response. 13

If your ECS is imbalanced, you could experience a large range of negative symptoms as a result. While the science is still out on this subject, CBD could help to alleviate these symptoms by attaching to the receptors and rebalancing your system. In general, the more your endocannabinoid system is imbalanced, the longer it will take to feel the effects.

While there’s no way to quantify how much of an imbalance you’re experiencing; you can probably gauge this yourself by assessing the severity of your symptoms.

Factor 5: Consistency

For some people, the positive effects come immediately. A lot of people will notice that they’re experiencing less stress, less tension, and better sleep after just one dose of CBD — but this is just from anecdotal reports. For others, it might take a few weeks to notice the powerful effects of CBD. So if you don’t feel it right away, be patient.

Some impatient people might give up after a few CBD doses and brush it off as snake oil that doesn’t work. While these people might be taking a bad-quality product, they’re also ignoring one of the key properties of CBD oil — take it consistently.

Regardless of what you’re feeling, the positive results come slowly. The key to getting the most benefits out of your CBD is consistency! A consistent, daily dose will eventually restore balance your ECS; and you’ll be glad you stuck with it.

Feeling Out How CBD Works for You

When you’re new to CBD, the first thing to know is that the effects take a few days to become noticeable. That means when you begin taking CBD every day, it’s good to be mindful of how your body responds to your daily CBD dosage. To discover its full effects, we recommend trying it for a full 30 days.

Your first 30 days on CBD is an important time to better understand your body and how it responds. Below we answer many of the most common beginners’ questions about CBD.

The potential therapeutic benefits that CBD oils and tinctures offer are becoming more recognized, making people more interested in getting started. The first 30 days can be a trial and error time in finding what works best for you, the individual. After reading these answers to the most common questions, you are likely to add a cannabis supplement into your everyday routine soon.

What Kind of CBD Should I Take?

For first time users, we always recommend starting with full spectrum CBD oil, which you take sublingually — which means a dropper of oil under your tongue for 30 to 60 seconds to let it absorb through the mucous membrane in your mouth.

Some people have trouble taking our CBD hemp oil under the tongue, and so they prefer the CBD capsules. They are also worth considering if you’re experiencing inflammation in the lower digestive tract, as capsules get further down into the gut.

People looking for pain relief in a specific area often apply a CBD lotion on the affected area, while avoiding the eyes and mucous membranes. For best results, we recommend pairing CBD lotion with sublingual oil, and using the same delivery methods at the same time everyday.

You’ll also always want to make sure whatever CBD product you are using has third party lab tests. The best companies have a QR code, and all of their company information, and testing lab information readily available to be reviewed before or after purchase. In order for CBD oil to work, you must first make sure that what you’re taking is real! If you can’t view the third party test results before making your purchase, then hold off until you can do more research.

Unfortunately, many unscrupulous brands sell fake CBD oil. 14 This is actually just hemp seed oil with a fake concentration listed on the bottle. You’ll also want to stay away from any brand that is making lofty health claims about its CBD oil. No medical claims regarding full spectrum CBD oil have been approved by the FDA, as of 2021. 15

What Time of Day Should I Take It?

This answer is different for everyone. The important thing is to find a time of day to best incorporate CBD into your daily routine. If you’re suffering from discomfort and inflammation during the day, maybe it’s best to take it in the morning. But if you’re using CBD because you’ve read reports that it can help you sleep, then taking it just before bedtime is your sweet spot.

How Often Should I Take CBD?

To begin, start taking CBD once per day, a full dropper of 25 milligrams, or 50 milligrams if you’re using our extra-strength CBD oils. See how you’re feeling and sleeping. For first time users, it can be good to “load dose” at first — taking larger than normal servings. That means, take a full dropper in the morning, and another full dropper before bedtime.

You will know if you have taken too much if you feel groggy in the morning, or if you experience diarrhea symptoms. 16 If you feel these side effects, dial back your current daily dosage to find something that works best for you.

How often you take CBD may also play a role in a drug test or work-related drug screenings. After taking CBD oil consistently for a period of weeks, the cannabinoids begin to build up within our systems, especially in fat cells, which could cause you to test positive during drug screenings. 17 If drug testing is a concern for your job, talk to your HR department before you start taking CBD consistently. You may also consider switching to a CBD topical, which has a far lower risk of showing up on a drug test.

How Long Does It Take For CBD Oil To Work?

It takes a few days for CBD to work, and it’s not something that you’ll notice right away. Be mindful of any pain, anxiety, and changes in sleep patterns as you work through your first week. Keep journal entries to track sleep and progress, and the amount of CBD you’re taking. This will help you be aware of the effects of CBD on your body. Understand that health benefits from natural supplements like CBD edibles, CBD tincture and oils don’t happen overnight. It takes time for the human body to adjust after implementing several different changes into our lifestyle. It also depends on the amount of CBD you’re taking to really experience the true effects of hemp derived CBD products .

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After One Month of CBD: How Will I Feel?

After a month of CBD usage, you’ll likely feel different. 18 But if you don’t believe us, try taking it for one month consistently, and then don’t take it for a week. Those bad feelings may return. That’s when you’ll know how CBD makes you feel, and you’ll be ready to order your CBD oil here. At Cornbread Hemp, we are passionate about producing our Flower-Only™ full spectrum, USDA organic hemp extract for consuming CBD in several different effective methods. And because our third-party lab partner tests every batch, you’ll never need to worry about potentially negative side effects from any harmful contaminants.

About the Author

Dr. Leslie Mudd, PharmD

A board certified oncology pharmacist with 25 years experience at the James Graham Brown Cancer Center in Louisville, Kentucky, Dr. Leslie Mudd now serves as the Cornbread Hemp resident pharmacist and medical expert. Read Dr. Mudd’s full author bio here.

References

1) Bruni N, Della Pepa C, Oliaro-Bosso S, Pessione E, Gastaldi D, Dosio F. Cannabinoid Delivery Systems for Pain and Inflammation Treatment. Molecules. 2018;23(10):2478. Published 2018 Sep 27. doi:10.3390/molecules23102478. Under the headings “Oral Route” and “Pulmonary Administration”

2) Bruni N, Della Pepa C, Oliaro-Bosso S, Pessione E, Gastaldi D, Dosio F. Cannabinoid Delivery Systems for Pain and Inflammation Treatment. Molecules. 2018;23(10):2478. Published 2018 Sep 27. doi:10.3390/molecules23102478. Under heading number 3.

3) Lucas CJ, Galettis P, Schneider J. The pharmacokinetics and the pharmacodynamics of cannabinoids. Br J Clin Pharmacol. 2018;84(11):2477-2482. doi:10.1111/bcp.13710. Discussed throughout the article.

4) Millar SA, Stone NL, Bellman ZD, Yates AS, England TJ, O’Sullivan SE. A systematic review of cannabidiol dosing in clinical populations. Br J Clin Pharmacol. 2019;85(9):1888-1900. doi:10.1111/bcp.14038. Under “Discussion” heading, 3rd paragraph

5) 10) Millar SA, Stone NL, Yates AS, O’Sullivan SE. A Systematic Review on the Pharmacokinetics of Cannabidiol in Humans. Front Pharmacol. 2018;9:1365. Published 2018 Nov 26. doi:10.3389/fphar.2018.01365. Last paragraph before Author Contributions

6) VanDolah HJ, Bauer BA, Mauck KF. Clinicians’ Guide to Cannabidiol and Hemp Oils. Mayo Clin Proc. 2019;94(9):1840-1851. doi:10.1016/j.mayocp.2019.01.003. Under the “Finding a Quality Product” and Table 3.

7) Pavlovic R, Nenna G, Calvi L, et al. Quality Traits of “Cannabidiol Oils”: Cannabinoids Content, Terpene Fingerprint and Oxidation Stability of European Commercially Available Preparations. Molecules. 2018;23(5):1230. Published 2018 May 20. doi:10.3390/molecules23051230. 5th paragraph in the introduction

8) Girdhar M, Sharma NR, Rehman H, Kumar A, Mohan A. Comparative assessment for hyperaccumulatory and phytoremediation capability of three wild weeds. 3 Biotech. 2014;4(6):579-589. doi:10.1007/s13205-014-0194-0. Under the heading “Hyperaccumalative action by Cannabis sativa”

9) Hemp Production. Hemp Production | Agricultural Marketing Service. Accessed July 1, 2020.

11) Millar SA, Stone NL, Yates AS, O’Sullivan SE. A Systematic Review on the Pharmacokinetics of Cannabidiol in Humans. Front Pharmacol. 2018;9:1365. Published 2018 Nov 26. doi:10.3389/fphar.2018.01365. Throughout article

12) Urasaki Y, Beaumont C, Workman M, Talbot JN, Hill DK, Le TT. Potency Assessment of CBD Oils by Their Effects on Cell Signaling Pathways. Nutrients. 2020;12(2):357. Published 2020 Jan 30. doi:10.3390/nu12020357. Throughout article

13) Pauli CS, Conroy M, Vanden Heuvel BD, Park SH. Cannabidiol Drugs Clinical Trial Outcomes and Adverse Effects. Front Pharmacol. 2020;11:63. Published 2020 Feb 25. doi:10.3389/fphar.2020.00063. Throughout article

14) VanDolah HJ, Bauer BA, Mauck KF. Clinicians’ Guide to Cannabidiol and Hemp Oils. Mayo Clin Proc. 2019;94(9):1840-1851. doi:10.1016/j.mayocp.2019.01.003. Under the “Finding a Quality Product”

15) Meissner H, Cascella M. Cannabidiol (CBD) [Updated 2020 Mar 9]. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2020 Jan-. Available from: . Under “Indications” heading

16) Millar SA, Stone NL, Bellman ZD, Yates AS, England TJ, O’Sullivan SE. A systematic review of cannabidiol dosing in clinical populations. Br J Clin Pharmacol. 2019;85(9):1888-1900. doi:10.1111/bcp.14038. Table 1, Table 2, and Table 3

17) Spindle TR, Cone EJ, Kuntz D, et al. Urinary Pharmacokinetic Profile of Cannabinoids Following Administration of Vaporized and Oral Cannabidiol and Vaporized CBD-Dominant Cannabis. J Anal Toxicol. 2020;44(2):109‐125. doi:10.1093/jat/bkz080

18) Shannon S, Lewis N, Lee H, Hughes S. Cannabidiol in Anxiety and Sleep: A Large Case Series. Perm J. 2019;23:18-041. doi:10.7812/TPP/18-041. After 1 month of administration, the trial showed improvement in anxiety scores.

All rights reserved. The statements made regarding these products have not been evaluated by the Food and Drug Administration. The health effects and benefits of CBD products have not been confirmed by FDA-approved research. Hemp derived CBD products are not intended to diagnose, treat, cure or prevent any disease. All information presented here is not meant as a substitute for or alternative to health information from licensed health care practitioners. Please consult your health care professional about potential interactions with prescription medication, or about other side effects before using any product. Taking too much CBD, and high doses of CBD may also cause undesired side effects. You should always consult with your doctor or another health care provider if you are considering making any changes to your lifestyle, diet or nutrition. Any CBD product is not intended for those who are pregnant or breastfeeding, please consult your doctor for more information before choosing to use CBD.

Cornbread Hemp works with cannabis plant suppliers who guarantee an equal to or less than 0.3 percent THC content. While there are no psychoactive side effects with these trace amounts of no more than 0.3% THC, it is possible that users may fail a drug test. Cornbread Hemp does not take any responsibility in the instance a customer fails a drug test while using any form of CBD products. Check state laws before travelling with any hemp derived CBD products.

How Long Does It Take for CBD Oil to Work? [The ANSWER!]

CBD, or cannabidiol, affects everyone differently. Independent variables such as dosage, body weight, and metabolism can influence your experience with the compound. Then there is the matter of how you consume CBD. The fastest method is intravenously, but since using a needle every day is not practical, inhalation via a vaporizer is the next best way. However, the full answer to the title question is much more complicated to explain.

Over the last few years, CBD has become the world’s trendiest health supplement. It is linked with improved mood, alleviation of pain, and reductions in the seizures associated with epilepsy. It is an exciting compound because it has an increasing body of scientific evidence to back up claims regarding its benefits.

However, you should not assume that a few milligrams of CBD will eliminate pain in a matter of minutes. Several factors influence the efficacy of the non-intoxicating cannabinoid; we analyze them below.

How Does CBD Work?

CBD must be absorbed into the bloodstream before being distributed through our endocannabinoid system (ECS). It is here that the cannabinoid interacts with the body’s receptors. This interaction is the driving force behind many of CBD’s perceived benefits.

This means that how CBD is absorbed is VERY important. Effective forms of CBD consumption not only get to the bloodstream faster, but they maintain substantial levels of the compound throughout the body. In other words, they offer high bioavailability. Additionally, the best ways to consume CBD involve bypassing the digestive system and metabolic process in the liver.

Factors That Impact CBD Absorption

The CBD form you use plays a huge role in how quickly it absorbs into your system. We look into consumption methods in greater detail a little later on. However, first, let’s look at four other important factors influencing how quickly CBD gets to work.

CBD Quality

Not all CBD products are created equally. We see sellers championing cannabidiol extracted from organic hemp, which is the bare minimum one would expect! Low-grade cannabidiol not only contains a smaller amount of CBD but also may include ingredients that reduce bioavailability.

Low-grade cannabidiol not only contains a smaller amount of CBD but also may include ingredients that reduce bioavailability.

The biggest issue to consider when judging the absorption time for CBD is the size of the particle in which it’s delivered. High-quality CBD sellers may invest in manufacturing processes such as microencapsulation, which breaks CBD into tiny particles. The result is faster absorption and higher efficacy.

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The Individual

The human body is remarkable, and our physiology can differ from person to person. This uniqueness comes into play when using CBD. If two individuals take the same CBD type, dose, and quality simultaneously, it may impact each person differently.

Also, if these two people tried the same experiment three months later, not only would the results differ between the two people again, they could also differ from their past results! Consequently, using CBD can sometimes require trial and error.

Body Weight

Currently, the only CBD-based medication approved by the FDA is the anti-epileptic, Epidiolex, which is prescribed to treat two rare forms of childhood epilepsy, namely Lennox-Gastaut syndrome and Dravet syndrome. While there are official guidelines relating to the appropriate dosage for Epidiolex, no other CBD-based products are FDA-approved. Consequently, there are no official guidelines related to their dosage. If you are unsure about what dose to begin with, speak with your doctor. They will be able to recommend an appropriate dose for you by taking factors such as your body weight into account.

Exploring the truth…

Metabolism

The rate of your body’s metabolism, known as the metabolic rate, involves breaking down and synthesizing compounds to help the body function properly. If you have a fast metabolism, it helps the body absorb CBD quicker.

However, if you metabolize any drug too quickly, you might not benefit from the prescribed dose. Therefore, you’ll need more CBD to have a similar effect as someone with a slower metabolism. You’ll also find that the effects of the cannabinoid wear off relatively quickly.

Things that impact our metabolism include age, genetics, digestive system health, and lifestyle.

Liver Function

Individuals with certain medical conditions may not process substances as well as healthier people. This is particularly the case when it comes to liver function. The liver is crucial in removing CBD from circulation and ensuring it is ready for export from the body. As a result, having impaired liver function dictates CBD’s effectiveness and how long it stays in the system.

A study published in the Journal of Clinical Pharmacology in 2019 analyzed the effect of cannabidiol on people with moderate to severe liver impairment. The researchers found that such individuals had greater blood CBD concentrations and lengthier clearance times after using 200mg of the cannabinoid compared to healthy control volunteers.

According to this study, CBD reaches the general circulation and remains there longer in people with liver impairment than without.

There is a reason why CBD companies make sure they use a carrier such as MCT oil in their products. Fatty foods significantly impact cannabidiol absorption.

A study published in Epilepsia in 2019 gave adults who had been prescribed CBD for seizures a dose of 99% pure cannabidiol capsules on two occasions. The first saw the volunteers take the compound on an empty stomach. The second involved using CBD after consuming a high-fat breakfast containing 840-860 calories, approximately 600 of which came from fat.

As CBD is fat-soluble, including a healthy fat source in your meal, such as fish high in omega-3 or avocado, can help absorption.

The researchers found that the maximum level of CBD in the blood was 14 times higher when consumed with the fatty breakfast than without. Overall, using CBD with food increased the amount of the cannabinoid in the body fourfold compared to using it in a fasted state.

As CBD is fat-soluble, including a healthy fat source in your meal, such as fish high in omega-3 or avocado, can further help absorption.

Dosage

You can increase the absorption rate of CBD and reduce the time taken to feel an effect by boosting the dosage. In general, the more you consume, the faster you’ll feel it. A study published in Frontiers in Pharmacology in 2018 found that increasing the CBD dose in an oral spray from 10mg to 20mg tripled absorption.

Yet, the researchers also found that the effects seem to have a ceiling in doses between 400mg and 800mg. This may be because tissues become saturated and can’t absorb any more CBD.

The revealing truth about CBD…

Method of CBD Consumption

The length of time it takes for CBD to work depends mostly on how you consume it. The cannabinoid only works when your body absorbs it. As a result, the CBD must make its way from the entry point into the bloodstream, where it can interact with cannabinoid receptors.

The method of consumption dictates the speed and level of absorption into your bloodstream. In general, the faster it gets to the bloodstream, the higher the bioavailability level.

Intravenous

This involves injecting CBD directly into the veins. Most people won’t have access to this method. Additionally, it is not a desirable method because not many people want to stab themselves with a needle every day. Sadly, it is unavoidable for patients with certain conditions. When you inject CBD, its bioavailability rate is 100%, and it works almost immediately.

Vaping & Smoking

Both methods involve inhaling CBD vapor directly into the lungs. The market is flooded with vaporizers that can heat CBD oil in seconds. Once you inhale the vapor, CBD and other cannabinoids reach your bloodstream via the alveoli in the lungs.

Overall, the vaporized CBD is absorbed into your bloodstream within a minute or so, although it could be a few minutes before you experience the full effects. As well as being the fastest non-intravenous method, inhalation also offers the highest level of bioavailability.

Vaping is a rapid method because the CBD can reach the bloodstream within a minute or so.

A 2009 study by Huestis, published in Chemistry & Biodiversity, found that vaping cannabinoids has a bioavailability rate of 56%. Other data places it between 34% and 46%.

Although not as popular as its THC equivalent, CBD flower is also available. You can purchase dozens of special marijuana strains high in CBD and low in THC. There are also hemp flower options too. A study published in Pharmaceuticals in 2020 found that smoking CBD resulted in peak plasma levels occurring within three minutes of inhalation.

However, combusting plant material can result in the release of carcinogenic substances. While a 2005 study suggested that cannabis smoke wasn’t causally linked to tobacco-related cancers, it was implicated in respiratory dysfunction.

Sublingually

If you don’t want to vape your CBD, sublingual consumption is the next best option. It involves placing drops of CBD oil beneath the tongue. Generally, it’s recommended to hold the oil there for up to 60 seconds for the best absorption.

The mucous membranes have a porous layer covering minuscule blood vessels, allowing the oil to absorb into your bloodstream faster. It can work in five minutes, although most users report experiencing effects in 15-25 minutes.

Several factors influence the absorption rate, which is why a 2012 study by Schoedel and Harrison, published in Current Pharmaceutical Design, placed the bioavailability rate anywhere between 12% and 35%.

Orally

As the name suggests, this involves consuming CBD through the mouth in a capsule, edible, or a CBD beverage. This method has a longer path to the bloodstream. It involves the salivary glands and the full stomach digestive process, which requires a journey through the liver, pancreas, and stomach.

It is relatively slow and can take up to 30 minutes to take effect. This taxing journey results in the loss of a lot of CBD. Huestis’ aforementioned 2009 study found that the bioavailability rate of orally consumed cannabinoids was between 4% and 20%.

Final Thoughts on Answering “How Long Does It Take for CBD Oil to Work?”

As you have discovered, there isn’t one answer that tells you how long CBD takes to work. How well CBD affects you depends on the product’s quality, not to mention your body composition, physical size, and physical condition.

Next, you have to look at the form of consumption. Aside from taking CBD intravenously, vaping the cannabinoid is the next fastest option and is also the best in terms of bioavailability.